Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604796 | 0.87 | THRA (0.36) | SLC6A5MAOBELANEPDE4BCYP2B6 | |
| SCHEMBL4603982 | 0.82 | TP53 (0.42) | SLC6A5MAOBPDE4BCYP2B6TP53 | |
| SCHEMBL4246097 | 0.78 | SLC6A5 (0.47) | SLC6A5PDE4BCYP2B6ALDH1A1SMN1; SMN2 | |
| SCHEMBL4245123 | 0.77 | SLC6A5 (0.58) | SLC6A5CYP2B6TP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL4604440 | 0.76 | MAOB (0.44) | MAOBELANEPDE4BCYP2B6ACHE | |
| SCHEMBL4249716 | 0.75 | SLC6A5 (0.58) | SLC6A5PDE4BCYP2B6TP53SMN1; SMN2 | |
| SCHEMBL4603140 | 0.75 | MAOB (0.43) | MAOBELANEPDE4BCYP2B6ACHE | |
| SCHEMBL2286794 | 0.74 | TSHR (0.68) | MAOBPDE4BCYP2B6TSHRMAPK1 | |
| SCHEMBL12799701 | 0.74 | MAOB (0.63) | MAOBPDE4BCYP2B6ACHEALDH1A1 | |
| SCHEMBL3288790 | 0.74 | CYP2B6 (0.56) | MAOBPDE4BCYP2B6ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |