Sugi Predict

Sugi Predict / Compounds / SCHEMBL4604913

SCHEMBL4604913

SCHEMBL4604913

NN1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MPO P05164 1/20 0.70
▸ ERCC1 P07992 1/20 0.63
▸ FEN1 P39748 1/20 0.63
▸ ERCC4 Q92889 1/20 0.63
▸ HEXA P06865 5/20 0.58
▸ HEXB P07686 5/20 0.58
▸ ALDH1A1 P00352 7/20 0.57
▸ KDM4E B2RXH2 4/20 0.57
▸ HPGD P15428 4/20 0.57
▸ HSD17B10 Q99714 3/20 0.57
▸ MEN1 O00255 2/20 0.57
▸ KMT2A Q03164 2/20 0.57
▸ CYP1B1 Q16678 1/20 0.57
▸ CES2 O00748 1/20 0.56
▸ BCHE P06276 1/20 0.56
▸ CES1 P23141 1/20 0.56
▸ MCL1 Q07820 1/20 0.56
▸ TYMS P04818 1/20 0.52
▸ NPSR1 Q6W5P4 1/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30530540 0.85 HPGD (0.56) MPOERCC1FEN1ERCC4HEXA
SCHEMBL15274249 0.85 HPGD (0.56) MPOERCC1FEN1ERCC4HEXA
SCHEMBL28583048 0.82 MPO (0.69) MPOERCC1FEN1ERCC4HEXA
SCHEMBL27752410 0.79 ERCC1 (0.65) ERCC1FEN1ERCC4HEXAHEXB
SCHEMBL22043114 0.78 MPO (0.48) MPOERCC1FEN1ERCC4ALDH1A1
SCHEMBL626365 0.78 MPO (0.48) MPOKDM4EMEN1KMT2ACES2
SCHEMBL29448054 0.78 MPO (0.48) MPOKDM4EMEN1KMT2ACES2
SCHEMBL24453236 0.77 ERCC1 (0.63) ERCC1FEN1ERCC4HEXAHEXB
SCHEMBL6734026 0.77 ERCC1 (0.63) ERCC1FEN1ERCC4HEXAHEXB
SCHEMBL21099252 0.77 ERCC1 (0.63) ERCC1FEN1ERCC4HEXAHEXB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112457313-B Naphthalimide-azacyclo-luminescent material and application thereof 深圳大学 2022-04-08 — — CN claimed
CN-112457313-A Naphthalimide-azacyclo-luminescent material and application thereof 深圳大学 2021-03-09 — — CN claimed
CN-108148045-B 1, 8-naphthamido (7-benzo [ c ] acridinyl) thiourea and preparation method and application thereof 广西中医药大学 2020-12-25 — — CN claimed
CN-108250182-B 1, 8-naphthamide (2-R group acridine group) thiourea silver ion probe and preparation method thereof 广西中医药大学 2020-10-23 — — CN claimed
CN-108299299-A The third amino of 4- -1,8- naphthalimide -7- benzos [c] acridine thiocarbamide and its preparation method and application 广西中医药大学 2018-07-20 — — CN claimed
CN-108250182-A 1,8- naphthoyl amido（2-R base acridinyls）Thiocarbamide silver ion probe and preparation method thereof 广西中医药大学 2018-07-06 — — CN claimed
CN-108148045-A 1,8- naphthoyls amido (7- benzos [c] acridinyl) thiocarbamide and its preparation method and application 广西中医药大学 2018-06-12 — — CN claimed
CN-107629044-A Naphthalimide aminothiazole class compound and its preparation method and application 西南大学 2018-01-26 — — CN claimed
CN-104946244-B Detect O2·‑Fluorescent molecular probe, its synthetic method and application 中国科学院宁波材料技术与工程研究所 2017-08-25 — — CN claimed
EP-1946777-A1 Substituted pyrazoline for preventing weight gain Laboratorios del Dr. Esteve S.A. (ES) 2008-07-23 — — EP claimed
EP-1946778-A1 Active substance combination for the treatment of diabetes Laboratorios del Dr. Esteve S.A. (ES) 2008-07-23 — — EP claimed
US-20070073056-A1 4-Substituted Pyrazoline Compounds, their Preparation and Use as Medicaments LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-03-29 — — US claimed
US-20070021398-A1 Substituted Pyrazoline Compounds, their Preparation and Use as Medicaments LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-01-25 — — US claimed
EP-1743888-A1 Carbonyl substituted pyrazoline compounds, their preparation and use as CB1 receptor modulators LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-01-17 — — EP claimed
CN-117396580-A Boron-containing cyclic light-emitting compound and color conversion film comprising the same 日东电工株式会社 2024-01-12 — — CN disclosed
EP-4286528-A1 METHOD AND DEVICE FOR DETECTING TRANSGLUTAMINASES Technische Universität Darmstadt (DE) 2023-12-06 — — EP disclosed
WO-2021029158-A1 SULFONAMIDE COMPOUND, NONIONIC PHOTOACID GENERATOR, AND PHOTOLITHOGRAPHY RESIN COMPOSITION サンアプロ株式会社 2021-02-18 — — WO disclosed
US-4939053-A Photosensitive member including azo compound MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1990-07-03 — — US disclosed
US-4219629-A P-Oxybenzoyl copolyesters comprising thiodiphenol components and having improved flexibility and solubility in organic solvents DART INDUSTRIES INC. (US) 1980-08-26 — — US disclosed
US-4197111-A 1,8-Naphthalimides and herbicide antidotes STAUFFER CHEMICAL COMPANY (US) 1980-04-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070073056-A1 4-Substituted Pyrazoline Compounds, their Preparation and Use as Medicaments P2RX4, PIR, P2RY4 MPO 671/4885ERCC1 2282/4885FEN1 1714/4885
US-20070021398-A1 Substituted Pyrazoline Compounds, their Preparation and Use as Medicaments PIR, SYMPK, P2RX5 MPO 410/4885ERCC1 2419/4885FEN1 1562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.