Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.63 |
| ▸ | FEN1 | P39748 | 1/20 | 0.63 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | HEXA | P06865 | 4/20 | 0.53 |
| ▸ | HEXB | P07686 | 4/20 | 0.53 |
| ▸ | TYMS | P04818 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29774569 | 0.85 | ALDH1A1 (0.56) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL27752410 | 0.79 | ERCC1 (0.65) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL28125149 | 0.78 | MEN1 (0.64) | KDM4EMEN1KMT2AMCL1MAPT | |
| SCHEMBL29385866 | 0.78 | POLB (0.48) | KDM4EMEN1KMT2ACES2BCHE | |
| SCHEMBL1771 | 0.78 | POLB (0.48) | KDM4EMEN1KMT2ACES2BCHE | |
| SCHEMBL24453236 | 0.77 | ERCC1 (0.63) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL862546 | 0.77 | ERCC1 (0.63) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL21099252 | 0.77 | ERCC1 (0.63) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL29089232 | 0.77 | ERCC1 (0.63) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL4604913 | 0.77 | MPO (0.70) | ERCC1FEN1ERCC4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116162061-A | Naphthalimide derivative fluorescent probe containing aldehyde group and preparation method and application thereof | 上海应用技术大学 | 2023-05-26 | — | — | CN | claimed |
| CN-115925613-A | Preparation method of near-infrared two-region squaraine type fluorescence imaging reagent, nano-composite and application thereof | 南昌大学 | 2023-04-07 | — | — | CN | claimed |
| CN-113088278-B | Room-temperature phosphorescent material and preparation method thereof | 华东理工大学 | 2022-10-21 | — | — | CN | claimed |
| CN-113150575-B | Near-infrared naphthalimide dye and preparation method and application thereof | 福州大学 | 2022-10-04 | — | — | CN | claimed |
| CN-109053572-B | 4-trifluoromethyl-6-bromo-2-substituted acetonitrile-1, 8-naphthalimide compound and preparation method and application thereof | 上海应用技术大学 | 2022-02-11 | — | — | CN | claimed |
| CN-110845495-B | Synthesis method of triplet photosensitizer | 齐齐哈尔大学 | 2022-01-18 | — | — | CN | claimed |
| CN-113150575-A | Near-infrared naphthalimide dye and preparation method and application thereof | 福州大学 | 2021-07-23 | — | — | CN | claimed |
| CN-110845495-A | Triplet photosensitizers and methods of synthesis | 齐齐哈尔大学 | 2020-02-28 | — | — | CN | claimed |
| CN-110452171-A | Fluorescence probe is used in a kind of hydrazine detection of naphthalimide precursor structure | UNIV LANZHOU | 2019-11-15 | — | — | CN | claimed |
| CN-110330478-A | Naphthalimide organic fluorescent gel compound and preparation method, organogel and application | 信阳师范学院 | 2019-10-15 | — | — | CN | claimed |
| CN-105778897-B | PH sensitive fluorescence dyes and its preparation method and application | 湖南大学 | 2017-12-26 | — | — | CN | claimed |
| CN-107501179-A | It is a kind of based on the water-soluble copper ion fluorescence probe material of naphthalimide dicarboxylic acids and its preparation and application | 兰州交通大学 | 2017-12-22 | — | — | CN | claimed |
| CN-107501527-A | A kind of high mobility semiconductor polymer and synthetic method based on 1,8 naphthalimides | 南昌大学 | 2017-12-22 | — | — | CN | claimed |
| CN-107164032-A | A kind of lubricating oil containing esters of acrylic acid POSS improved silica nano-particles and preparation method thereof | 山东沾化莱斯特石油化工有限公司 | 2017-09-15 | — | — | CN | claimed |
| CN-107118155-A | Fragrant naphthoyl imide compounds of ethanol base 1,8 of one kind 4 and its preparation method and application | 上海应用技术大学 | 2017-09-01 | — | — | CN | claimed |
| CN-107056704-A | A kind of hypochlorite ion's fluorescence probe of lysosome targeting and its application | 郑州大学 | 2017-08-18 | — | — | CN | claimed |
| CN-107033879-A | It is a kind of to be used to detect fluorescence probe of glutathione and its preparation method and application | 许昌学院 | 2017-08-11 | — | — | CN | claimed |
| CN-107022349-A | Cytochrome oxidase CYP1A1 specificity fluorescent probes and preparation method and application | 中国科学院大连化学物理研究所 | 2017-08-08 | — | — | CN | claimed |
| CN-106867521-A | A kind of new naphthalimide H2S fluorescence probes and preparation method and application | 叶凤池 | 2017-06-20 | — | — | CN | claimed |
| CN-106590628-A | Specific fluorescent probe substrate of bilirubin metabolic enzyme UGT1A1 and preparation and application thereof | 中国科学院大连化学物理研究所 | 2017-04-26 | — | — | CN | claimed |