Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | KDM1A | O60341 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606839 | 0.90 | KCNQ3 (0.50) | SLC6A2SLC6A4KDM1AMAOBLMNA | |
| SCHEMBL3323648 | 0.86 | KCNQ3 (0.54) | SLC6A2SLC6A4KDM1AKCNQ3KCNQ2 | |
| SCHEMBL4607106 | 0.82 | SLC6A4 (0.43) | SLC6A2SLC6A4KDM1ASLC9A1DGAT1 | |
| SCHEMBL4607726 | 0.82 | HRH3 (0.46) | SLC6A2SLC6A4KDM1AMAOBDGAT1 | |
| SCHEMBL4604971 | 0.82 | SLC6A2 (0.52) | SLC6A2SLC6A4KDM1AMAOBRAB9A | |
| SCHEMBL4608244 | 0.81 | SIRT2 (0.40) | SLC6A2SLC6A4RAB9AKCNQ3KCNQ2 | |
| SCHEMBL4608166 | 0.81 | SLC6A2 (0.42) | SLC6A2SLC6A4MAOBFFAR1 | |
| SCHEMBL4606990 | 0.80 | ALDH1A1 (0.49) | SLC6A2SLC6A4KDM1AKCNQ3KCNQ2 | |
| SCHEMBL4608380 | 0.80 | SIRT2 (0.52) | SLC9A1 | |
| SCHEMBL4371167 | 0.80 | SLC6A4 (0.43) | SLC6A2SLC6A4KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | claimed |
| US-6639107-B1 | Potentiating glutamate receptor function | ELI LILLY AND COMPANY | 2003-10-28 | — | — | US | claimed |
| EP-1246797-A1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-10-09 | — | — | EP | claimed |
| WO-2001042203-A1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-06-14 | — | — | WO | claimed |
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | disclosed |
| US-6639107-B1 | Potentiating glutamate receptor function | ELI LILLY AND COMPANY | 2003-10-28 | — | — | US | disclosed |
| EP-1246797-A1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001042203-A1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-06-14 | — | — | WO | disclosed |