Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.50 |
| ▸ | CNR1 | P21554 | 5/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460619 | 0.83 | TRPM4 (0.52) | ALOX5TRPM4NQO1PTPN22MEN1 | |
| SCHEMBL27930163 | 0.79 | ALOX5 (0.52) | CNR2CNR1L3MBTL1ALOX5ENPP1 | |
| SCHEMBL374808 | 0.78 | ALOX5 (0.52) | ALOX5TRPM4NQO1PTPN22 | |
| SCHEMBL488939 | 0.74 | ACHE (0.50) | CNR2CNR1L3MBTL1ENPP1KMT2A | |
| SCHEMBL5459938 | 0.73 | CNR2 (0.53) | CNR2CNR1ACLYL3MBTL1ALOX5 | |
| SCHEMBL5478449 | 0.73 | NQO1 (0.46) | ALOX5TRPM4NQO1PTPN22SIRT1 | |
| SCHEMBL7909976 | 0.73 | CYP2A6 (0.46) | CNR2CNR1L3MBTL1ENPP1KMT2A | |
| SCHEMBL5461208 | 0.73 | CYP11B1 (0.59) | ACLYL3MBTL1 | |
| SCHEMBL26348798 | 0.73 | CNR2 (0.50) | CNR2CNR1ACLYL3MBTL1ALOX5 | |
| SCHEMBL3170245 | 0.73 | KMT2A (0.46) | ALOX5NQO1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39663-E1 | Electron-deficient nitrogen heterocycle-substituted fluorescein dyes | APPLERA CORPORATION (US) | 2007-05-29 | — | — | US | disclosed |
| EP-1196640-B1 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | APPLERA CORP (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-1196640-A2 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | Applera Corporation (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001057264-A2 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | APPLERA CORPORATION (US) | 2001-08-09 | — | — | WO | disclosed |
| US-6221604-B1 | CONJUGATED TO SUBSTRATES SUCH AS NUCLEOSIDES OR NUCLEOTIDES AND USED AS DETECTION LABELS IN MOLECULAR BIOLOGY EXPERIMENTS; ENERGY TRANSFER DYE | PE CORPORATION | 2001-04-24 | — | — | US | disclosed |