Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.43 |
| ▸ | JMJD6 | Q6NYC1 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515409 | 0.88 | BAZ2B (0.46) | BAZ2BBAZ2AJMJD6ADORA3ADORA2A | |
| SCHEMBL19186 | 0.88 | JMJD6 (0.44) | BAZ2BBAZ2AJMJD6ADORA3ADORA2A | |
| SCHEMBL862681 | 0.83 | ADORA3 (0.45) | BAZ2BBAZ2AJMJD6ADORA3ADORA2A | |
| SCHEMBL1862734 | 0.83 | KDM4E (0.43) | BAZ2BBAZ2AJMJD6ADORA3ADORA2A | |
| SCHEMBL460661 | 0.80 | LMNA (0.34) | KDM4EGAARAB9ALMNA | |
| SCHEMBL31265247 | 0.79 | TSHR (0.41) | BAZ2BBAZ2AJMJD6ADORA3ADORA2A | |
| SCHEMBL16106085 | 0.79 | ADORA2A (0.34) | BAZ2BBAZ2AJMJD6ADORA3ADORA2A | |
| SCHEMBL28553124 | 0.79 | BAZ2B (0.46) | BAZ2BBAZ2AJMJD6ADORA3ADORA2A | |
| SCHEMBL1085956 | 0.78 | ADORA2A (0.36) | ADORA2AADORA1GAANPC1RAB9A | |
| SCHEMBL31265255 | 0.78 | JMJD6 (0.41) | BAZ2BBAZ2AJMJD6TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629288-B2 | Method for the regioselective synthesis of 1-alky1-3-haloalkyl-pyrazole-4-carboxylic acid derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-8629288-B2 | Method for the regioselective synthesis of 1-alky1-3-haloalkyl-pyrazole-4-carboxylic acid derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-8629288-B2 | Method for the regioselective synthesis of 1-alky1-3-haloalkyl-pyrazole-4-carboxylic acid derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-8592605-B2 | Method for the regioselective synthesis of 1-Alkyl-3-haloalkyl-pyrazole-4-carboxylic acid derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-26 | — | — | US | disclosed |
| US-20130197239-A1 | Method for the Regioselective Synthesis of 1-Alkyl-3-Haloalkyl-Pyrazole-4-Carboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2013-08-01 | — | — | US | disclosed |
| US-20130197239-A1 | Method for the Regioselective Synthesis of 1-Alkyl-3-Haloalkyl-Pyrazole-4-Carboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2013-08-01 | — | — | US | disclosed |
| US-20130197239-A1 | Method for the Regioselective Synthesis of 1-Alkyl-3-Haloalkyl-Pyrazole-4-Carboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2013-08-01 | — | — | US | disclosed |
| EP-2257532-B1 | METHOD FOR REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL-1-PYRAZOL-4-CARBONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2013-05-29 | — | — | EP | disclosed |
| EP-2257532-B1 | METHOD FOR REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL-1-PYRAZOL-4-CARBONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2013-05-29 | — | — | EP | disclosed |
| US-8350053-B2 | Process for the regioselective preparation of 1-alkyl-3-haloalkylpyrazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-01-08 | — | — | US | disclosed |
| EP-2100883-A1 | Method for regioselective synthesis of 1-alkyl-3-haloalkyl-1-pyrazol-4-carbonic acid derivatives | Bayer CropScience AG (DE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2009106230-A2 | METHOD FOR THE REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL–PYROAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTENGESELLSCHAFT (DE) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009106230-A2 | METHOD FOR THE REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL–PYROAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTENGESELLSCHAFT (DE) | 2009-09-03 | — | — | WO | disclosed |
| EP-2057126-A2 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2009-05-13 | — | — | EP | disclosed |
| US-7501527-B2 | Method for the production of fluoromethyl-substituted heterocycles | BAYER CROPSCIENCE GMBH (DE) | 2009-03-10 | — | — | US | disclosed |
| US-7501527-B2 | Method for the production of fluoromethyl-substituted heterocycles | BAYER CROPSCIENCE GMBH (DE) | 2009-03-10 | — | — | US | disclosed |
| US-7501527-B2 | Method for the production of fluoromethyl-substituted heterocycles | BAYER CROPSCIENCE GMBH (DE) | 2009-03-10 | — | — | US | disclosed |
| WO-2008022777-A2 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008022777-A2 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-02-28 | — | — | WO | disclosed |
| US-20060276656-A1 | Method for the production of fluoromethyl-substituted heterocycles | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197239-A1 | Method for the Regioselective Synthesis of 1-Alkyl-3-Haloalkyl-Pyrazole-4-Carboxylic Acid Derivatives | ATL3, HCAR3, AADAC | BAZ2B 576/4885BAZ2A 581/4885JMJD6 628/4885 |
| US-20060276656-A1 | Method for the production of fluoromethyl-substituted heterocycles | FLI1, CBR3, CBR1 | BAZ2B 3142/4885BAZ2A 3559/4885JMJD6 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.