Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141 | 0.83 | IRAK4 (0.35) | GAASMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3258066 | 0.83 | GAA (0.33) | GAAALDH1A1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL19321638 | 0.83 | ADORA2A (0.38) | GAARAB9APOLBL3MBTL1 | |
| SCHEMBL11893139 | 0.83 | RAB9A (0.34) | PPARAGAAALDH1A1SMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL1032497 | 0.81 | IRAK4 (0.34) | GAALMNAPOLB | |
| Hydrochloric Acid SCHEMBL8932295 | 0.81 | IRAK4 (0.34) | GAALMNAPOLB | |
| SCHEMBL28726067 | 0.81 | IRAK4 (0.35) | GAA | |
| SCHEMBL23142702 | 0.80 | MAPT (0.40) | GAAALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5652284 | 0.80 | GAA (0.35) | GAAALDH1A1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL13095835 | 0.80 | GAA (0.44) | GAAALDH1A1SMN1; SMN2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818683-B | 2-pyridine substituted urea structure small molecule compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2023-04-14 | — | — | CN | disclosed |
| US-20210378242-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, LLC (US) | 2021-12-09 | — | — | US | disclosed |
| CN-110818683-A | 2-pyridine substituted urea structure small molecule compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2020-02-21 | — | — | CN | disclosed |
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |
| US-10405548-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION LLC (US) | 2019-09-10 | — | — | US | disclosed |
| US-10344026-B2 | Compositions and methods of targeting mutant K-ras | NANTBIO, INC. (US) | 2019-07-09 | — | — | US | disclosed |
| US-20180201610-A1 | COMPOSITIONS AND METHODS OF TARGETING MUTANT K-RAS | NANTBIO, INC. | 2018-07-19 | — | — | US | disclosed |
| US-9949482-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, LLC (US) | 2018-04-24 | — | — | US | disclosed |
| US-9949482-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, LLC (US) | 2018-04-24 | — | — | US | disclosed |
| US-9783536-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| US-8536089-B2 | For controlling phytopathogenic diseases; synergistic | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-17 | — | — | US | disclosed |
| US-8269013-B2 | Substituted pyrazole inhibitors of c-Met protein kinase | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-09-18 | — | — | US | disclosed |
| EP-2332411-B1 | Fungicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2012-07-25 | — | — | EP | disclosed |
| CN-102388045-A | Compounds for the treatment of hepatitis c | BRISTOL MYERS SQUIBB CO | 2012-03-21 | — | — | CN | disclosed |
| EP-2332411-A1 | Fungicidal compositions | Syngenta Participations AG (CH) | 2011-06-15 | — | — | EP | disclosed |
| EP-1778013-B1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-01-26 | — | — | EP | disclosed |
| WO-2010138663-A1 | SUBSTITUTED PYRAZOLE INHIBITORS OF C-MET PROTEIN KINASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-12-02 | — | — | WO | disclosed |
| US-20100305155-A1 | SUBSTITUTED PYRAZOLE INHIBITORS OF C-MET PROTEIN KINASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-12-02 | — | — | US | disclosed |
| US-20080070785-A1 | For controlling phytopathogenic diseases; synergistic | SYNGENTA CROP PROTECTION, INC. (US) | 2008-03-20 | — | — | US | disclosed |
| US-20080070785-A1 | For controlling phytopathogenic diseases; synergistic | SYNGENTA CROP PROTECTION, INC. (US) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210378242-A1 | FUNGICIDAL COMPOSITIONS | PIK3C3, CYP51A1, CYP1B1 | PPARA 2097/4885PPARG 2039/4885GAA 56/4885 |
| US-20100305155-A1 | SUBSTITUTED PYRAZOLE INHIBITORS OF C-MET PROTEIN KINASE | MET, BRAF, DMPK | PPARA 2374/4885PPARG 1409/4885GAA 4110/4885 |
| US-10344026-B2 | Compositions and methods of targeting mutant K-ras | KRAS, NRAS, HRAS | PPARA 3613/4885PPARG 2489/4885GAA 1776/4885 |
| US-20180201610-A1 | COMPOSITIONS AND METHODS OF TARGETING MUTANT K-RAS | KRAS, NRAS, HRAS | PPARA 3613/4885PPARG 2489/4885GAA 1776/4885 |
| US-10405548-B2 | Fungicidal compositions | PIK3C3, CYP51A1, CYP1B1 | PPARA 2097/4885PPARG 2039/4885GAA 56/4885 |
| US-20080070785-A1 | For controlling phytopathogenic diseases; synergistic | BROX, EPM2A, MANBA | PPARA 2022/4885PPARG 2281/4885GAA 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.