Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 12/20 | 0.55 |
| ▸ | CA12 | O43570 | 11/20 | 0.55 |
| ▸ | CA1 | P00915 | 11/20 | 0.55 |
| ▸ | CA9 | Q16790 | 8/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 5/20 | 0.48 |
| ▸ | CA5A | P35218 | 5/20 | 0.48 |
| ▸ | CA7 | P43166 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15243619 | 1.00 | THRB (0.57) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL13593687 | 1.00 | THRB (0.57) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL16358235 | 1.00 | THRB (0.57) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL14747304 | 1.00 | THRB (0.57) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL6972799 | 1.00 | THRB (0.57) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL14882448 | 1.00 | THRB (0.57) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL22516447 | 1.00 | THRB (0.57) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL22592286 | 1.00 | THRB (0.57) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL20711502 | 1.00 | THRB (0.57) | THRBCYP2D6HSD17B10TSHRNR3C1 | |
| SCHEMBL13396025 | 1.00 | THRB (0.57) | THRBCYP2D6HSD17B10TSHRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305284-B1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | UNIV MICHIGAN STATE (US) | 2008-11-12 | — | — | EP | claimed |
| EP-1305284-A4 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | UNIV MICHIGAN STATE (US) | 2005-08-03 | — | — | EP | claimed |
| EP-1305284-A1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | MICHIGAN STATE UNIVERSITY (US) | 2003-05-02 | — | — | EP | claimed |
| US-6423867-B1 | FROM TRI-O-ACETYL-D-ERYTHRO-4-PENTULOSONIC ACID ESTERS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2002-07-23 | — | — | US | claimed |
| US-20020026071-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES, OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | claimed |
| US-20020026073-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | claimed |
| US-20020026072-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2002-02-28 | — | — | US | claimed |
| US-20020026074-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERS | 2002-02-28 | — | — | US | claimed |
| US-20020019542-A1 | Process and intermediate compounds for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY BOARD OF TRUSTEES OPERATING | 2002-02-14 | — | — | US | claimed |
| US-20020019561-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-14 | — | — | US | claimed |
| WO-2002010130-A1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | MICHIGAN STATE UNIVERSITY (US) | 2002-02-07 | — | — | WO | claimed |
| US-11730752-B2 | Use of NMN for the prevention and/or treatment of joint pain induced by physical activity, and corresponding compositions | NUVAMID SA (CH) | 2023-08-22 | — | — | US | disclosed |
| US-20230210746-A1 | ANTI-AGING COSMETIC COMPOSITIONS COMPRISING NMN | NUVAMID SA (CH) | 2023-07-06 | — | — | US | disclosed |
| US-20230172959-A1 | USE OF NMN FOR THE PREVENTION AND/OR TREATMENT OF A BACK PAIN AND CORRESPONDING COMPOSITIONS | NUVAMID SA (CH) | 2023-06-08 | — | — | US | disclosed |
| US-20230060438-A1 | USE OF NMN FOR THE PREVENTION AND/OR TREATMENT OF JOINT PAIN INDUCED BY PHYSICAL ACTIVITY, AND CORRESPONDING COMPOSITIONS | NUVAMID SA (CH) | 2023-03-02 | — | — | US | disclosed |
| US-20020026071-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES, OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | disclosed |
| US-20020026073-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-28 | — | — | US | disclosed |
| US-20020019542-A1 | Process and intermediate compounds for the preparation of pyrrolidines | MICHIGAN STATE UNIVERSITY BOARD OF TRUSTEES OPERATING | 2002-02-14 | — | — | US | disclosed |
| US-20020019561-A1 | Process and intermediate compounds for the preparation of pyrrolidines | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2002-02-14 | — | — | US | disclosed |
| WO-2002010130-A1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | MICHIGAN STATE UNIVERSITY (US) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172959-A1 | USE OF NMN FOR THE PREVENTION AND/OR TREATMENT OF A BACK PAIN AND CORRESPONDING COMPOSITIONS | NNT, NAMPT, UTRN | THRB 1104/4885CYP2D6 3978/4885HSD17B10 3411/4885 |
| US-20230060438-A1 | USE OF NMN FOR THE PREVENTION AND/OR TREATMENT OF JOINT PAIN INDUCED BY PHYSICAL ACTIVITY, AND CORRESPONDING COMPOSITIONS | NNT, NAMPT, NMUR1 | THRB 4002/4885CYP2D6 3544/4885HSD17B10 2773/4885 |
| US-20020026073-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | THRB 2246/4885CYP2D6 795/4885HSD17B10 3135/4885 |
| US-20020026071-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | THRB 2246/4885CYP2D6 795/4885HSD17B10 3135/4885 |
| US-11730752-B2 | Use of NMN for the prevention and/or treatment of joint pain induced by physical activity, and corresponding compositions | NNT, NAMPT, NMUR1 | THRB 4002/4885CYP2D6 3544/4885HSD17B10 2773/4885 |
| US-20230210746-A1 | ANTI-AGING COSMETIC COMPOSITIONS COMPRISING NMN | NCL, POLN, CUTA | THRB 4627/4885CYP2D6 4519/4885HSD17B10 1763/4885 |
| US-20020019542-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | THRB 2246/4885CYP2D6 795/4885HSD17B10 3135/4885 |
| US-20020026074-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | THRB 2246/4885CYP2D6 795/4885HSD17B10 3135/4885 |
| US-20020026072-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | THRB 2246/4885CYP2D6 795/4885HSD17B10 3135/4885 |
| US-20020019561-A1 | Process and intermediate compounds for the preparation of pyrrolidines | UMPS, DUT, DPYD | THRB 2246/4885CYP2D6 795/4885HSD17B10 3135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.