Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23689892 | 0.79 | EPHX2 (0.50) | KMT2AALDH1A1TRPV1EPHX2NR1H4 | |
| SCHEMBL9449259 | 0.77 | ALDH1A1 (0.61) | KMT2AALDH1A1MEN1HTTHIF1A | |
| SCHEMBL16563109 | 0.77 | ALDH5A1 (0.52) | KMT2AALDH1A1MEN1TRPV1EPHX2 | |
| SCHEMBL5367543 | 0.77 | ALDH1A1 (0.71) | KMT2AALDH1A1MEN1HTTHIF1A | |
| SCHEMBL21600610 | 0.76 | EPHX2 (0.47) | KMT2AMEN1TRPV1EPHX2NR1H4 | |
| SCHEMBL9448941 | 0.75 | ALDH1A1 (0.54) | KMT2AALDH1A1MEN1HTTHIF1A | |
| SCHEMBL9448908 | 0.74 | ALDH1A1 (0.61) | KMT2AALDH1A1MEN1HTTHIF1A | |
| SCHEMBL4475347 | 0.74 | NPC1 (0.60) | TRPV1EPHX2NR1H4NPC1RAB9A | |
| SCHEMBL20015846 | 0.74 | EPHX2 (0.57) | TRPV1EPHX2NR1H4NPC1RAB9A | |
| SCHEMBL20134914 | 0.74 | ALDH1A1 (0.61) | KMT2AALDH1A1MEN1HTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080292608-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2008-11-27 | — | — | US | disclosed |
| US-20080292608-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2008-11-27 | — | — | US | disclosed |
| EP-1945633-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2008-07-23 | — | — | EP | disclosed |
| US-20070244130-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2007-10-18 | — | — | US | disclosed |
| US-20070244130-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2007-10-18 | — | — | US | disclosed |
| WO-2007056497-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |
| EP-1749003-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005116016-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080292608-A1 | Compounds and Compositions as Ppar Modulators | PPARG, PPARA, PPARD | KMT2A 3705/4885ALDH1A1 1696/4885MEN1 4844/4885 |
| US-20070244130-A1 | Compounds and Compositions as Ppar Modulators | PPARG, PPARA, PPARD | KMT2A 3698/4885ALDH1A1 1651/4885MEN1 4853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.