Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.70 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.68 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.68 |
| ▸ | LTA4H | P09960 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430078 | 0.82 | HRH3 (0.72) | HRH3KEAP1NFE2L2LTA4HKDM4E | |
| SCHEMBL28144525 | 0.81 | HRH3 (0.70) | HRH3KEAP1NFE2L2LTA4HKDM4E | |
| SCHEMBL110426 | 0.81 | KEAP1 (1.00) | HRH3KEAP1NFE2L2LTA4HKDM4E | |
| SCHEMBL14608491 | 0.81 | HRH3 (0.70) | HRH3KEAP1NFE2L2LTA4HKDM4E | |
| SCHEMBL17974260 | 0.81 | HRH3 (0.70) | HRH3KEAP1NFE2L2LTA4HKDM4E | |
| SCHEMBL185585 | 0.81 | HRH3 (0.70) | HRH3KEAP1NFE2L2LTA4HKDM4E | |
| SCHEMBL11236618 | 0.80 | HRH3 (0.64) | HRH3KEAP1NFE2L2LTA4HKDM4E | |
| SCHEMBL4547156 | 0.79 | HRH3 (0.79) | HRH3KEAP1NFE2L2LTA4HKDM4E | |
| Hydrochloric Acid SCHEMBL5803566 | 0.79 | KEAP1 (0.96) | HRH3KEAP1NFE2L2LTA4HKDM4E | |
| Hydrochloric Acid SCHEMBL17544448 | 0.79 | HRH3 (0.68) | HRH3KEAP1NFE2L2LTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1527042-B1 | METHOD FOR PRODUCING AMINOALKOXY BENZYLAMINES AND AMINOALKOXY BENZONITRILES AS INTERMEDIATES | BASF SE (DE) | 2008-07-23 | — | — | EP | disclosed |
| US-7256312-B2 | Method for producing aminoalkoxy benzylamines and aminoalkoxy benzonitriles as intermediates | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-14 | — | — | US | disclosed |
| US-20050256340-A1 | Method for producing aminoalkoxy benzylamines and aminoalkoxy benzonitriles as intermediates | BASF AKTIENGESELLSCHAFT (DE) | 2005-11-17 | — | — | US | disclosed |
| EP-1527042-A2 | METHOD FOR PRODUCING AMINOALKOXY BENZYLAMINES AND AMINOALKOXY BENZONITRILES AS INTERMEDIATES | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-04 | — | — | EP | disclosed |
| WO-2004013082-A2 | METHOD FOR PRODUCING AMINOALKOXY BENZYLAMINES AND AMINOALKOXY BENZONITRILES AS INTERMEDIATES | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256340-A1 | Method for producing aminoalkoxy benzylamines and aminoalkoxy benzonitriles as intermediates | BCAT1, BCAT2, ALKBH3 | HRH3 51/4885KEAP1 1332/4885NFE2L2 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.