Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 1.00 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.70 |
| ▸ | LTA4H | P09960 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5803566 | 0.98 | KEAP1 (0.96) | KEAP1NFE2L2HRH3LTA4HKDM4E | |
| SCHEMBL110784 | 0.91 | KEAP1 (0.83) | KEAP1NFE2L2HRH3LTA4HKDM4E | |
| SCHEMBL23928219 | 0.85 | HRH3 (0.77) | KEAP1NFE2L2HRH3LTA4HKCNH2 | |
| Hydrochloric Acid SCHEMBL30876469 | 0.84 | HRH3 (0.74) | KEAP1NFE2L2HRH3LTA4HKCNH2 | |
| SCHEMBL8430078 | 0.82 | HRH3 (0.72) | KEAP1NFE2L2HRH3LTA4HKDM4E | |
| SCHEMBL781665 | 0.82 | KEAP1 (0.70) | KEAP1NFE2L2HRH3LTA4HKDM4E | |
| SCHEMBL2424129 | 0.81 | KEAP1 (0.69) | KEAP1NFE2L2HRH3LTA4HKDM4E | |
| SCHEMBL874547 | 0.81 | HRH3 (0.70) | KEAP1NFE2L2HRH3LTA4HKDM4E | |
| SCHEMBL7973439 | 0.81 | KEAP1 (0.67) | KEAP1NFE2L2HRH3LTA4HMAOB | |
| SCHEMBL14608491 | 0.81 | HRH3 (0.70) | KEAP1NFE2L2HRH3LTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057916-B | Preparation method of lubricating oil antioxidant ashless dispersant | 中国石油天然气股份有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-110794046-B | Method for detecting 2,4, 5-trifluoro-3-methoxybenzoyl chloride in moxifloxacin intermediate | 珠海润都制药股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-114057916-A | Preparation method of antioxidant ashless dispersant for lubricating oil | 中国石油天然气股份有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-110794046-A | Method for detecting 2,4, 5-trifluoro-3-methoxybenzoyl chloride in moxifloxacin intermediate | 珠海润都制药股份有限公司 | 2020-02-14 | — | — | CN | claimed |
| WO-2006051079-A1 | PROCESS FOR PREPARING ITOPRIDE HYDROCHLORIDE | ERREGIERRE S.P.A. (IT) | 2006-05-18 | — | — | WO | claimed |
| US-12606520-B2 | Calpain-2 inhibitor compounds and methods of treatment | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2026-04-21 | — | — | US | disclosed |
| US-20250259704-A1 | SYSTEMS AND METHODS FOR CELL-FREE ITERATIVE SITE SATURATION MUTAGENESIS AND ITS APPLICATION FOR THE DIRECTED EVOLUTION OF ENZYMES CATALYZING UNNATURAL REACTIONS | U.S. DEPARTMENT OF ENERGY | 2025-08-14 | — | — | US | disclosed |
| CN-116947645-B | Low-carbon environment-friendly method for synthesizing primary amine by taking halohydrocarbon as raw material | 台州市创源工业技术有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-118895514-A | Amide derivative and preparation method thereof | 济宁学院 | 2024-11-05 | — | — | CN | disclosed |
| US-12049461-B2 | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections | GILEAD SCIENCES, INC. (US) | 2024-07-30 | — | — | US | disclosed |
| US-12024506-B2 | Compounds | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2024-07-02 | — | — | US | disclosed |
| US-12024506-B2 | Compounds | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2024-07-02 | — | — | US | disclosed |
| WO-2006011696-A1 | METHOD FOR PREPARING 4-[2-(DIMETHYLAMINO)ETHOXY]BENZYLAMINE AS ITOPRIDE HYDROCLORIDE SALT MEDIATE | IL YANG PHARM. CO., LTD (KR) | 2006-02-02 | — | — | WO | disclosed |
| WO-2006011696-A1 | METHOD FOR PREPARING 4-[2-(DIMETHYLAMINO)ETHOXY]BENZYLAMINE AS ITOPRIDE HYDROCLORIDE SALT MEDIATE | IL YANG PHARM. CO., LTD (KR) | 2006-02-02 | — | — | WO | disclosed |
| US-20050256340-A1 | Method for producing aminoalkoxy benzylamines and aminoalkoxy benzonitriles as intermediates | BASF AKTIENGESELLSCHAFT (DE) | 2005-11-17 | — | — | US | disclosed |
| EP-1527042-A2 | METHOD FOR PRODUCING AMINOALKOXY BENZYLAMINES AND AMINOALKOXY BENZONITRILES AS INTERMEDIATES | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-04 | — | — | EP | disclosed |
| WO-2004013082-A2 | METHOD FOR PRODUCING AMINOALKOXY BENZYLAMINES AND AMINOALKOXY BENZONITRILES AS INTERMEDIATES | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-12 | — | — | WO | disclosed |
| EP-0306827-B1 | AMIDE COMPOUNDS, PROCESS FOR PREPARING THE SAME, AND COMPOSITION FOR ACTIVATING GASTRIC MOTOR FUNCTION CONTAINING THE SAME | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1991-09-04 | — | — | EP | disclosed |
| US-4983633-A | Amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0306827-A1 | Amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1989-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12049461-B2 | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections | NR3C1, NR3C2, NR4A1 | KEAP1 3435/4885NFE2L2 2768/4885HRH3 168/4885 |
| US-12606520-B2 | Calpain-2 inhibitor compounds and methods of treatment | CAPN2, CAPN1, CAPNS1 | KEAP1 621/4885NFE2L2 274/4885HRH3 2482/4885 |
| US-20050256340-A1 | Method for producing aminoalkoxy benzylamines and aminoalkoxy benzonitriles as intermediates | BCAT1, BCAT2, ALKBH3 | KEAP1 1332/4885NFE2L2 599/4885HRH3 51/4885 |
| US-12024506-B2 | Compounds | KRAS, NRAS, HRAS | KEAP1 390/4885NFE2L2 2421/4885HRH3 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.