Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 3/20 | 0.57 |
| ▸ | F2 | P00734 | 2/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.52 |
| ▸ | LPL | P06858 | 6/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15252314 | 0.86 | CA1 (0.55) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1684672 | 0.83 | CA1 (0.61) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1141383 | 0.80 | CA2 (0.55) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8289771 | 0.76 | CA1 (0.53) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4914268 | 0.76 | F2 (0.52) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9888401 | 0.76 | LIPG (0.58) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL16899331 | 0.75 | CA1 (0.71) | CA1CA2CA9 | |
| SCHEMBL14141265 | 0.75 | NPC1 (0.59) | CA1CA2CA9CA12 | |
| SCHEMBL26000408 | 0.75 | LPL (0.67) | F11F2PRSS1PRSS2PRSS3 | |
| SCHEMBL15585542 | 0.75 | CA2 (0.50) | F11F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | disclosed |
| US-6639107-B1 | Potentiating glutamate receptor function | ELI LILLY AND COMPANY | 2003-10-28 | — | — | US | disclosed |