SCHEMBL4607987

SCHEMBL4607987

CCCCCC/C=C/P(=O)(OC1CCCCC1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A2 O00482 1/20 0.37
NR5A1 Q13285 1/20 0.37
SOAT2 O75908 1/20 0.36
SOAT1 P35610 1/20 0.36
MAPT P10636 2/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
NAAA Q02083 2/20 0.35
FAAH O00519 3/20 0.34
EPHX2 P34913 2/20 0.34
CES1 P23141 1/20 0.34
LPAR3 Q9UBY5 2/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4607989 1.00 NR5A2 (0.37) NR5A2NR5A1SOAT2SOAT1MAPT
SCHEMBL4606349 0.78 AOX1 (0.44) SOAT2SOAT1MAPTTP53CYP3A4
SCHEMBL4606338 0.78 AOX1 (0.44) SOAT2SOAT1MAPTTP53CYP3A4
SCHEMBL12814148 0.74 NPSR1 (0.35) MAPTCYP3A4ALDH1A1LMNAHTT
SCHEMBL4609010 0.73 SOAT2 (0.46) SOAT2SOAT1MAPTTP53CYP3A4
SCHEMBL4609004 0.73 SOAT2 (0.46) SOAT2SOAT1MAPTTP53CYP3A4
SCHEMBL776498 0.73 AOX1 (0.38) MAPTTSHRALDH1A1LMNAHTT
SCHEMBL779274 0.72 ALOX15 (0.41) MAPTTSHRALDH1A1LMNAHTT
SCHEMBL19602996 0.71 FAAH (0.42) MAPTALDH1A1NAAAFAAHLPAR3
SCHEMBL4878268 0.71 SOAT2 (0.47) SOAT2SOAT1TSHRFAAHEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1369422-B1 PROCESS FOR PREPARATION OF ALKENYLPHOSPHINE OXIDES OR ALKENYLPHOSPHINIC ACID ESTERS JAPAN SCIENCE & TECH AGENCY (JP) 2008-07-23 EP disclosed
US-7135583-B2 Process for preparation of alkenylphosphine oxides or alkenylphosphinic esters JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2006-11-14 US disclosed
US-20040059146-A1 Process for preparation of alkenylphosphine oxides or alkenylphosphinic esters JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2004-03-25 US disclosed
EP-1369422-A1 PROCESS FOR PREPARATION OF ALKENYLPHOSPHINE OXIDES OR ALKENYLPHOSPHINIC ACID ESTERS Japan Science and Technology Corporation (JP) 2003-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040059146-A1 Process for preparation of alkenylphosphine oxides or alkenylphosphinic esters PHOSPHO1, AGPS, AGPAT5 NR5A2 2960/4885NR5A1 1762/4885SOAT2 132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.