Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.58 |
| ▸ | CNR2 | P34972 | 4/20 | 0.58 |
| ▸ | CNR1 | P21554 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | PPARD | Q03181 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28215864 | 0.93 | XDH (0.68) | XDHALOX5ALDH1A1CYP3A4PTGS1 | |
| SCHEMBL219534 | 0.93 | XDH (0.68) | XDHALOX5ALDH1A1CYP3A4PTGS1 | |
| Bicarbonate SCHEMBL28309849 | 0.86 | XDH (0.59) | XDHALOX5ALDH1A1CYP3A4PTGS1 | |
| Estragole SCHEMBL1230287 | 0.84 | ALDH1A1 (0.67) | XDHALOX5ALDH1A1CYP3A4PTGS1 | |
| Phenol SCHEMBL15570258 | 0.83 | XDH (0.56) | XDHALOX5ALDH1A1CYP3A4PTGS1 | |
| Methyleugenol SCHEMBL1440046 | 0.83 | ALDH1A1 (0.73) | XDHALOX5ALDH1A1CYP3A4PTGS1 | |
| Eugenol SCHEMBL2883800 | 0.80 | ALDH1A1 (0.90) | XDHALOX5ALDH1A1CYP3A4PTGS1 | |
| SCHEMBL10451531 | 0.78 | XDH (0.68) | XDHALOX5ALDH1A1CYP3A4PTGS1 | |
| SCHEMBL14368297 | 0.76 | GABRA1 (0.79) | XDHALOX5ALDH1A1CYP3A4PTGS1 | |
| SCHEMBL2431475 | 0.76 | ESR1 (0.63) | XDHALOX5ALDH1A1CYP3A4PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945693-A1 | POLYARYLATE-SILOXANE COPOLYMERS | Momentive Performance Materials Inc. (US) | 2008-07-23 | — | — | EP | claimed |
| WO-2007047083-A1 | POLYARYLATE-SILOXANE COPOLYMERS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2007-04-26 | — | — | WO | claimed |
| US-20070083026-A1 | Polyarylate-siloxane copolymers | GENERAL ELECTRIC COMPANY (US) | 2007-04-12 | — | — | US | claimed |