Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.37 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10770284 | 0.87 | MAPK1 (0.43) | TSHRMAPK1PDE7AMAPTLMNA | |
| SCHEMBL4439375 | 0.82 | F11 (0.33) | TSHRMAPTSMN1; SMN2NPC1HPGD | |
| SCHEMBL4608484 | 0.76 | KCNMA1 (0.36) | TSHRMAPK1PDE7APDE7BMEN1 | |
| SCHEMBL28383967 | 0.69 | ALDH1A1 (0.41) | TSHRMAPK1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL23167082 | 0.68 | MAPK1 (0.47) | TSHRMAPK1PDE7APDE7BMAPT | |
| SCHEMBL29764490 | 0.68 | MAPK1 (0.59) | TSHRMAPK1PDE7APDE7BMAPT | |
| SCHEMBL165577 | 0.68 | MAPK1 (0.59) | TSHRMAPK1PDE7APDE7BMAPT | |
| SCHEMBL17339128 | 0.68 | TDP1 (0.42) | TSHRMAPK1MAPTRAB9AVCAM1 | |
| SCHEMBL11516745 | 0.67 | MAPK1 (0.69) | TSHRMAPK1PDE7APDE7BMAPT | |
| SCHEMBL3196901 | 0.67 | ALDH1A1 (0.47) | TSHRMAPK1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |