Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809081 | 0.82 | EPHX2 (0.51) | KMT2AMEN1L3MBTL1EPHX2HSD11B1 | |
| SCHEMBL3809079 | 0.82 | HSD11B1 (0.51) | KMT2AMEN1L3MBTL1EPHX2HSD11B1 | |
| SCHEMBL241938 | 0.81 | L3MBTL1 (0.58) | KMT2AMEN1L3MBTL1EPHX2HSD11B1 | |
| SCHEMBL3809076 | 0.80 | L3MBTL1 (0.49) | KMT2AMEN1L3MBTL1EPHX2HSD11B1 | |
| SCHEMBL238713 | 0.80 | L3MBTL1 (0.57) | KMT2AMEN1L3MBTL1EPHX2HSD11B1 | |
| SCHEMBL1675682 | 0.79 | KMT2A (0.74) | KMT2AMEN1L3MBTL1EPHX2HSD11B1 | |
| SCHEMBL19808151 | 0.76 | HSD11B1 (0.54) | KMT2AMEN1L3MBTL1EPHX2HSD11B1 | |
| SCHEMBL3809265 | 0.76 | L3MBTL1 (0.45) | KMT2AMEN1L3MBTL1EPHX2HSD11B1 | |
| SCHEMBL3809268 | 0.76 | CYP3A4 (0.49) | KMT2AMEN1L3MBTL1EPHX2HSD11B1 | |
| SCHEMBL2536584 | 0.76 | RAB9A (0.57) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948190-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007051810-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2007-05-10 | — | — | WO | disclosed |