Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962170 | 0.87 | HTR2A (0.31) | HTR2AHTR2C | |
| SCHEMBL5583422 | 0.82 | CNR2 (0.33) | NUDT1 | |
| SCHEMBL4596883 | 0.80 | GPBAR1 (0.37) | — | |
| SCHEMBL5595803 | 0.79 | CNR2 (0.33) | NUDT1 | |
| SCHEMBL4609617 | 0.77 | AQP1 (0.36) | — | |
| SCHEMBL4607693 | 0.76 | KDM4E (0.36) | — | |
| SCHEMBL5595955 | 0.75 | NPC1 (0.34) | — | |
| SCHEMBL4596995 | 0.75 | HTR1A (0.39) | HTR2AHTR2C | |
| SCHEMBL4596991 | 0.74 | HTR2A (0.37) | HTR2AHTR2C | |
| SCHEMBL5583692 | 0.73 | FGFR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |