Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962170 | 0.86 | HTR2A (0.31) | FGFR1GRIA1CACNG8 | |
| SCHEMBL4607851 | 0.82 | DRD1 (0.34) | — | |
| SCHEMBL5586547 | 0.77 | MEN1 (0.36) | — | |
| SCHEMBL27703068 | 0.76 | CD274 (0.40) | — | |
| SCHEMBL27723634 | 0.76 | HTR1A (0.38) | — | |
| SCHEMBL27723752 | 0.76 | HTR7 (0.37) | — | |
| SCHEMBL27723765 | 0.75 | HTR1A (0.33) | — | |
| SCHEMBL27723655 | 0.75 | PLA2G7 (0.37) | — | |
| SCHEMBL27703039 | 0.75 | DPP4 (0.38) | — | |
| SCHEMBL27723629 | 0.73 | AHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007509174-A | — | — | 2007-04-12 | — | — | JP | claimed |
| EP-1675840-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2006-07-05 | — | — | EP | claimed |
| WO-2005044812-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH A CORPORATION OF THE STATE OF DELAWARE (US) | 2005-05-19 | — | — | WO | claimed |