Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595955 | 0.76 | NPC1 (0.34) | HTR1A | |
| SCHEMBL5586519 | 0.76 | NPC1 (0.35) | DRD2 | |
| SCHEMBL5583652 | 0.73 | ENPP3 (0.40) | — | |
| SCHEMBL6374163 | 0.72 | BCAT1 (0.33) | CNR2HTR1ASLC9A1 | |
| SCHEMBL218508 | 0.72 | TRPA1 (0.52) | CNR2NUDT1TRPA1ATM | |
| SCHEMBL30834716 | 0.72 | TRPA1 (0.52) | CNR2NUDT1TRPA1ATM | |
| Fluorene SCHEMBL18316006 | 0.71 | MAOA (0.48) | TRPA1ATMHTR1A | |
| SCHEMBL5583692 | 0.70 | FGFR1 (0.31) | — | |
| Ammonia Solution, Strong SCHEMBL15862222 | 0.70 | TRPA1 (0.50) | CNR2NUDT1TRPA1ATM | |
| Ammonia Solution, Strong SCHEMBL22444763 | 0.70 | TRPA1 (0.50) | CNR2NUDT1TRPA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007509174-A | — | — | 2007-04-12 | — | — | JP | claimed |
| EP-1675840-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2006-07-05 | — | — | EP | claimed |
| WO-2005044812-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH A CORPORATION OF THE STATE OF DELAWARE (US) | 2005-05-19 | — | — | WO | claimed |