Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | AHR | P35869 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973722 | 0.99 | MEN1 (0.68) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| Zinc Chloride SCHEMBL30135274 | 0.95 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL11693570 | 0.95 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL11690434 | 0.94 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL27922925 | 0.89 | MAPT (0.61) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL9653899 | 0.88 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| Trifluoromethanesulfonic Acid SCHEMBL11057927 | 0.88 | MEN1 (0.60) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL11081067 | 0.87 | MEN1 (0.60) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL14588703 | 0.87 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL11427553 | 0.84 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1113779-A1 | METHOD FOR DYEING FIBRES CONTAINING KERATIN USING STABLE DIAZONIUM SALTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2001-07-11 | — | — | EP | claimed |
| WO-2000015184-A1 | METHOD FOR DYEING FIBRES CONTAINING KERATIN USING STABLE DIAZONIUM SALTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-03-23 | — | — | WO | claimed |
| US-20240003922-A1 | POLYMERIC GEL COMPOSITIONS FOR DETECTION OF THC | Genesee Valley Innovations, LLC | 2024-01-04 | — | — | US | disclosed |
| US-9791399-B2 | Derivatization of carbon | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2017-10-17 | — | — | US | disclosed |
| US-20140332412-A1 | DERIVATIZATION OF CARBON | SCHLUMBERGER TECHNOLOGY COPORATION (US) | 2014-11-13 | — | — | US | disclosed |
| WO-2014096232-A1 | PROCESS OF ELECTROCHEMICALLY REDUCING AN AROMATIC DIAZONIUM SALT ON A SUBSTRATE AND SUBSTRATE OBTAINED THEREBY | NATIONAL UNIVERSITY OF IRELAND MAYNOOTH (IE) | 2014-06-26 | — | — | WO | disclosed |
| WO-2013093882-A2 | DERIVATIZATION OF CARBON | SCHLUMBERGER TECHNOLOGY B.V. (NL) | 2013-06-27 | — | — | WO | disclosed |
| EP-1517668-B1 | GENTLE OXIDATIVE HAIR DYEING METHODS | HENKEL AG & CO KGAA (DE) | 2008-10-08 | — | — | EP | disclosed |
| EP-1517668-A2 | GENTLE OXIDATIVE HAIR DYING METHODS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004002439-A2 | GENTLE OXIDATIVE HAIR DYING METHODS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-01-08 | — | — | WO | disclosed |
| EP-1220654-A1 | HAIR COLORATION METHOD | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-07-10 | — | — | EP | disclosed |
| EP-1113779-A1 | METHOD FOR DYEING FIBRES CONTAINING KERATIN USING STABLE DIAZONIUM SALTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2001-07-11 | — | — | EP | disclosed |
| WO-2001026616-A1 | HAIR COLORATION METHOD | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-04-19 | — | — | WO | disclosed |
| WO-2000015184-A1 | METHOD FOR DYEING FIBRES CONTAINING KERATIN USING STABLE DIAZONIUM SALTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-03-23 | — | — | WO | disclosed |
| EP-0410750-B1 | Use of Interleukin-4 for increasing numbers of neutrophils and for treating myeloid or monocytoid leukaemia. | SCHERING CORP (US) | 1995-03-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140332412-A1 | DERIVATIZATION OF CARBON | FTH1, CBR1, SDHB | MEN1 1759/4885KMT2A 961/4885SMN1; SMN2 4435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.