Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811254 | 0.90 | ALDH1A1 (0.36) | ALDH1A1LMNAF10HPGDHRH3 | |
| SCHEMBL3814369 | 0.82 | HRH3 (0.39) | ALDH1A1HPGDMAPTGLAHRH3 | |
| SCHEMBL12576932 | 0.81 | HRH3 (0.37) | ALDH1A1LMNAF10HPGDHRH3 | |
| SCHEMBL3819063 | 0.80 | LMNA (0.54) | ALDH1A1LMNAHPGDHRH3KMT2A | |
| SCHEMBL3811550 | 0.78 | HPGD (0.56) | ALDH1A1LMNAF10HPGDMAPT | |
| SCHEMBL12640409 | 0.74 | CA2 (0.38) | ALDH1A1LMNAHPGDHRH3KMT2A | |
| SCHEMBL3812022 | 0.74 | HDAC1 (0.46) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL3811439 | 0.73 | LMNA (0.37) | ALDH1A1LMNAHPGDHRH3KMT2A | |
| SCHEMBL3811818 | 0.73 | AOC3 (0.40) | ALDH1A1LMNAHPGDMAPTHRH3 | |
| SCHEMBL3811384 | 0.73 | CCR5 (0.40) | ALDH1A1HRH3KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948190-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007051810-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2007-05-10 | — | — | WO | disclosed |