Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6130076 | 1.00 | AGTR1 (0.48) | AGTR1AGTR2MME | |
| Elisartan SCHEMBL1560942 | 0.93 | AGTR1 (0.52) | AGTR1AGTR2 | |
| Elisartan SCHEMBL615370 | 0.93 | AGTR1 (0.52) | AGTR1AGTR2 | |
| Elisartan SCHEMBL489081 | 0.92 | AGTR1 (0.53) | AGTR1AGTR2 | |
| Elisartan SCHEMBL489079 | 0.92 | AGTR1 (0.53) | AGTR1AGTR2 | |
| Elisartan SCHEMBL615371 | 0.92 | AGTR1 (0.52) | AGTR1AGTR2 | |
| Elisartan SCHEMBL29595840 | 0.92 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL3430082 | 0.87 | AGTR1 (0.42) | AGTR1AGTR2MME | |
| SCHEMBL12990879 | 0.86 | AGTR2 (0.53) | AGTR1AGTR2 | |
| SCHEMBL4655085 | 0.85 | AGTR1 (0.41) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877373-A2 | BIPHENYLAZETIDINONE CHOLESTEROL ABSORPTION INHIBITORS | Microbia, Inc. (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006121861-A2 | BIPHENYLAZETIDINONE CHOLESTEROL ABSORPTION INHIBITORS | MICROBIA, INC. (US) | 2006-11-16 | — | — | WO | disclosed |