Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5086321 | 0.83 | ALKBH3 (0.36) | LMNAALKBH3HTR2ASLC6A4KCNH2 | |
| SCHEMBL3664944 | 0.74 | RAPGEF4 (0.35) | ALKBH3LRRK2 | |
| SCHEMBL10798128 | 0.74 | LMNA (0.39) | LMNA | |
| SCHEMBL4609341 | 0.72 | ALKBH3 (0.34) | LMNAALKBH3MAOAMAOB | |
| SCHEMBL2737284 | 0.69 | LMNA (0.50) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL3412996 | 0.69 | ALKBH3 (0.36) | LMNAALKBH3LRRK2MAOAMAOB | |
| SCHEMBL6668337 | 0.69 | TRPA1 (0.60) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL30320821 | 0.69 | TRPA1 (0.60) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL5086316 | 0.68 | ALKBH3 (0.35) | LMNAHTR2BALKBH3LRRK2MAOA | |
| SCHEMBL3412999 | 0.67 | ALKBH3 (0.34) | ALKBH3LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948649-A2 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007014290-A2 | FUNGICIDAL CARBOXAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-02-01 | — | — | WO | disclosed |