Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 14/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 14/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP27B1 | O15528 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402751 | 0.89 | LMNA (0.33) | UBE2MDCUN1D1LMNAKMT2ACYP1A2 | |
| SCHEMBL13438298 | 0.78 | MAPK1 (0.41) | UBE2MDCUN1D1LMNAKMT2ACYP1A2 | |
| SCHEMBL11771891 | 0.77 | — | — | |
| SCHEMBL912644 | 0.76 | UBE2M (0.36) | UBE2MDCUN1D1LMNAKMT2ACYP1A2 | |
| SCHEMBL10989916 | 0.76 | UBE2M (0.34) | UBE2MDCUN1D1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL9662206 | 0.74 | DCUN1D1 (0.39) | UBE2MDCUN1D1LMNAKMT2ACYP27B1 | |
| Ammonia Solution, Strong SCHEMBL10363130 | 0.74 | UBE2M (0.36) | UBE2MDCUN1D1LMNAKMT2ACYP1A2 | |
| SCHEMBL18402647 | 0.74 | DCUN1D1 (0.39) | UBE2MDCUN1D1LMNAKMT2A | |
| SCHEMBL7430903 | 0.74 | UBE2M (0.36) | UBE2MDCUN1D1LMNAKMT2ACYP1A2 | |
| SCHEMBL9375491 | 0.74 | UBE2M (0.36) | UBE2MDCUN1D1LMNAKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448393-B1 | DEPROTECTING CARBOXYLIC ACID GROUP, DEHALOGENATING AND SULFIDING WITH HETEROARYL-THIO SUBSTITUTED COMPOUND PRODUCING 3-THIOMETHYLCEPHEM COMPOUNDS; CHEMICAL INTERMEDIATES TO ANTIBIOTICS, SUCH AS CEFAZOLIN AND CEFTRIAXONE | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2002-09-10 | — | — | US | claimed |
| EP-1028118-A1 | PROCESS FOR PRODUCING 3-CEPHEM COMPOUNDS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2000-08-16 | — | — | EP | claimed |
| EP-0300546-B1 | Process for the preparation of cephem compounds and cephalosporin derivatives | GIST BROCADES NV (NL) | 1995-08-09 | — | — | EP | claimed |
| US-4921954-A | FROM SULFOXIDE INTERMEDIATE | GIST-BROCADES N.V. (NL) | 1990-05-01 | — | — | US | claimed |
| EP-0300546-A1 | Process for the preparation of cephem compounds and cephalosporin derivatives | GIST-BROCADES N.V. (NL) | 1989-01-25 | — | — | EP | claimed |
| EP-0099580-B1 | NEW 1-OXA-1-DETHIA-CEPHALOSPORIN DERIVATIVES | MERCK & CO. INC. (US) | 1987-10-14 | — | — | EP | claimed |
| US-4534898-A | 1-Oxa-1-dethia-cephalosporin derivatives | MERCK & CO., INC. (US) | 1985-08-13 | — | — | US | claimed |
| EP-0121499-A2 | Cephalosporins, their preparation and pharmaceutical compositions | CIBA-GEIGY AG (CH) | 1984-10-10 | — | — | EP | claimed |
| US-4464366-A | Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group | CIBA GEIGY CORPORATION (US) | 1984-08-07 | — | — | US | claimed |
| EP-0099580-A1 | New 1-oxa-1-dethia-cephalosporin derivatives | MERCK & CO. INC. (US) | 1984-02-01 | — | — | EP | claimed |
| US-4374134-A | Cephalosporin compounds with terminal aminocarboxylic acid groupings and anti-bacterial use thereof | CIBA-GEIGY CORPORATION (US) | 1983-02-15 | — | — | US | claimed |
| EP-0059683-A2 | 7-Acylamido-3-cephem-4-carboxylic acids, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1982-09-08 | — | — | EP | claimed |
| EP-0000500-B1 | CEPHALOSPRIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1982-04-28 | — | — | EP | claimed |
| US-4313945-A | 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping | CIBA-GEIGY CORPORATION (US) | 1982-02-02 | — | — | US | claimed |
| US-4286088-A | Process for preparing 7-aminocephalosporins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-08-25 | — | — | US | claimed |
| EP-0031794-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1981-07-08 | — | — | EP | claimed |
| EP-0022245-A2 | Aminothiadiazolyl derivatives, process for their preparation, pharmaceutical compositions containing them;starting compounds and process for their preparation | CIBA-GEIGY AG (CH) | 1981-01-14 | — | — | EP | claimed |
| EP-0016296-A1 | Cephalosporin derivatives, process for their preparation, compositions containing them, and intermediates and their preparation | CIBA-GEIGY AG (CH) | 1980-10-01 | — | — | EP | claimed |
| EP-0003960-A1 | 6-Substituted thia-aza-compounds, their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1979-09-19 | — | — | EP | claimed |
| EP-0000500-A2 | Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | claimed |