Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 12/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 12/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4609640 | 0.74 | UBE2M (0.36) | UBE2MDCUN1D1LMNAKMT2ACYP1A2 | |
| SCHEMBL912644 | 0.74 | UBE2M (0.36) | UBE2MDCUN1D1LMNAKMT2AALDH1A1 | |
| SCHEMBL10996032 | 0.74 | CYP1A2 (0.57) | LMNAKMT2AALDH1A1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL10363130 | 0.73 | UBE2M (0.36) | UBE2MDCUN1D1LMNAKMT2AALDH1A1 | |
| SCHEMBL18402647 | 0.73 | DCUN1D1 (0.39) | UBE2MDCUN1D1LMNAKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9662206 | 0.73 | DCUN1D1 (0.39) | UBE2MDCUN1D1LMNAKMT2AALDH1A1 | |
| SCHEMBL3742869 | 0.72 | LMNA (0.71) | UBE2MDCUN1D1LMNAKMT2AALDH1A1 | |
| SCHEMBL13314661 | 0.72 | UBE2M (0.38) | UBE2MDCUN1D1LMNAKMT2A | |
| SCHEMBL9601574 | 0.72 | DCUN1D1 (0.35) | UBE2MDCUN1D1LMNAKMT2AALDH1A1 | |
| SCHEMBL10197492 | 0.72 | UBE2M (0.40) | UBE2MDCUN1D1LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251299-B1 | Cephalosporin compounds, processes for their preparation and antibacterial agents | KAKEN PHARMA CO LTD (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-4883879-A | CHEMICAL INTERMEDIATES | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1989-11-28 | — | — | US | disclosed |
| US-4822786-A | Cephalosporin compounds, and antibacterial agents | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0251299-A2 | Cephalosporin compounds, processes for their preparation and antibacterial agents | Kaken Pharmaceutical Co., Ltd. (JP) | 1988-01-07 | — | — | EP | disclosed |