SCHEMBL4610271

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5751664	0.85	KCNH2 (0.57)	CYP2A6KCNH2GHSRSLC5A1SLC5A2
	SCHEMBL12803437	0.84	CYP2A6 (0.46)	CYP2A6KCNH2LOXL2HRH3GHSR
	SCHEMBL6419682	0.80	NPC1 (0.39)	KCNH2HRH3SLC5A1SLC5A2P2RX7
	SCHEMBL4109180	0.72	KCNH2 (0.75)	CYP2A6KCNH2PGRCYP19A1
	SCHEMBL4240032	0.72	AR (0.59)	LOXL2ARP2RX7
	SCHEMBL7118321	0.69	P2RX7 (0.39)	KCNH2HSD17B10P2RX7
	SCHEMBL91062	0.67	CYP2A6 (1.00)	CYP2A6KCNH2LOXL2TSHRHSD17B10
	SCHEMBL1344068	0.67	LOXL2 (0.65)	CYP2A6KCNH2LOXL2HRH3SAE1
	SCHEMBL694505	0.66	PARP1 (0.45)	LOXL2HRH3AR
	SCHEMBL7402930	0.65	MEN1 (0.53)	LOXL2HRH3ARSAE1UBA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.