Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 8/20 | 0.44 |
| ▸ | KDM1B | Q8NB78 | 3/20 | 0.44 |
| ▸ | DPP4 | P27487 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461045 | 1.00 | HTR2C (0.44) | HTR2CHTR2AHTR2BKDM1AKDM1B | |
| SCHEMBL461044 | 1.00 | HTR2C (0.44) | HTR2CHTR2AHTR2BKDM1AKDM1B | |
| SCHEMBL179110 | 0.80 | KDM1A (0.66) | HTR2CHTR2AHTR2BKDM1AKDM1B | |
| SCHEMBL12064742 | 0.78 | HTR2C (0.46) | HTR2CHTR2AHTR2BKDM1AKDM1B | |
| SCHEMBL29941500 | 0.74 | CHRNB2 (0.47) | KDM1AKDM1BDPP4CHRNB2CHRNB4 | |
| SCHEMBL470620 | 0.74 | CHRNB2 (0.47) | KDM1AKDM1BDPP4CHRNB2CHRNB4 | |
| SCHEMBL179045 | 0.73 | KDM1A (0.63) | HTR2CHTR2AHTR2BKDM1AKDM1B | |
| SCHEMBL8102755 | 0.72 | HTR2C (0.60) | HTR2CHTR2AHTR2BDPP4 | |
| SCHEMBL8102751 | 0.72 | HTR2C (0.60) | HTR2CHTR2AHTR2BDPP4 | |
| SCHEMBL21057790 | 0.71 | DPP4 (0.41) | HTR2CHTR2AHTR2BKDM1AKDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |