Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.66 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.66 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13186510 | 0.86 | HTR2C (0.49) | KDM1AKDM1BHTR2CCHRNB2CHRNB4 | |
| SCHEMBL178948 | 0.85 | KDM1A (0.60) | KDM1AKDM1BHTR2CCHRNB2CHRNB4 | |
| SCHEMBL12064742 | 0.85 | HTR2C (0.46) | KDM1AKDM1BHTR2CCHRNB2CHRNA4 | |
| SCHEMBL29941500 | 0.80 | CHRNB2 (0.47) | KDM1AKDM1BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL470620 | 0.80 | CHRNB2 (0.47) | KDM1AKDM1BCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL461043 | 0.80 | HTR2C (0.44) | KDM1AKDM1BHTR2CCHRNB2CHRNB4 | |
| SCHEMBL461044 | 0.80 | HTR2C (0.44) | KDM1AKDM1BHTR2CCHRNB2CHRNB4 | |
| SCHEMBL461045 | 0.80 | HTR2C (0.44) | KDM1AKDM1BHTR2CCHRNB2CHRNB4 | |
| SCHEMBL179045 | 0.79 | KDM1A (0.63) | KDM1AKDM1BHTR2CCHRNB2CHRNB4 | |
| SCHEMBL18998216 | 0.76 | KDM1A (0.47) | KDM1AKDM1BHTR2CCHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059014-A1 | Compounds for the Treatment of Metabolic Disorders | PROSIDION LIMITED (GB) | 2012-03-08 | — | — | US | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059014-A1 | Compounds for the Treatment of Metabolic Disorders | GPR119, FFAR2, GPBAR1 | KDM1A 4195/4885KDM1B 2993/4885HTR2C 1350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.