Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462997 | 0.86 | LDHA (0.39) | GPR119HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2934379 | 0.82 | GPR119 (0.49) | GPR119 | |
| SCHEMBL3188715 | 0.81 | POLB (0.40) | FAAHGPR119 | |
| SCHEMBL461743 | 0.80 | POLB (0.41) | FAAHGPR119 | |
| SCHEMBL13336514 | 0.80 | SMN1; SMN2 (0.39) | FAAHGPR119 | |
| SCHEMBL3178836 | 0.77 | GPR119 (0.43) | GPR119 | |
| SCHEMBL461611 | 0.77 | ALDH1A1 (0.38) | GPR119 | |
| SCHEMBL609296 | 0.76 | GPR119 (0.55) | FAAHGPR119 | |
| SCHEMBL457366 | 0.76 | GPR119 (0.60) | FAAHGPR119 | |
| SCHEMBL470616 | 0.76 | DPP4 (0.36) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |