Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610502 | 0.84 | EPHX2 (0.38) | PTGS2ALOX15NPC1ALDH1A1RAB9A | |
| SCHEMBL3210607 | 0.81 | NAAA (0.49) | PTGS2ALOX15NPC1ALDH1A1RAB9A | |
| SCHEMBL2085350 | 0.80 | MTNR1A (0.38) | NPC1ALDH1A1RAB9A | |
| SCHEMBL1751392 | 0.79 | FFAR1 (0.39) | PTGS2NPC1ALDH1A1RAB9A | |
| SCHEMBL3150081 | 0.77 | PTGS2 (0.45) | PTGS2ALOX15 | |
| SCHEMBL3150086 | 0.77 | PTGS2 (0.45) | PTGS2ALOX15 | |
| SCHEMBL2173697 | 0.77 | PTGS2 (0.51) | PTGS2FAAH | |
| SCHEMBL3439038 | 0.77 | PTGS2 (0.44) | PTGS2 | |
| SCHEMBL3439039 | 0.77 | PTGS2 (0.44) | PTGS2 | |
| SCHEMBL2084552 | 0.76 | EPHX2 (0.38) | PTGS2ALOX15NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781297-B1 | NOVEL BIAROMATIC COMPOUNDS THAT ACTIVATE PPAR TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2008-10-15 | — | — | EP | claimed |