Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.33 |
| ▸ | ACACA | Q13085 | 5/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46143 | 0.89 | ACACB (0.33) | ACACBACACAHTR2AHTR2CHTR2B | |
| SCHEMBL17703555 | 0.88 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL45953 | 0.87 | CYP1A2 (0.32) | ACACBACACA | |
| SCHEMBL46124 | 0.85 | ACACB (0.32) | ACACBACACA | |
| SCHEMBL45965 | 0.84 | ACACB (0.33) | ACACBACACA | |
| SCHEMBL46130 | 0.84 | ACACB (0.33) | ACACBACACA | |
| SCHEMBL12072064 | 0.83 | OPRM1 (0.32) | — | |
| SCHEMBL46099 | 0.82 | — | — | |
| SCHEMBL45948 | 0.82 | CYP1A2 (0.32) | — | |
| SCHEMBL19139856 | 0.81 | ACACB (0.32) | ACACBACACAHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771365-B2 | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-26 | — | — | US | disclosed |
| US-9771365-B2 | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-26 | — | — | US | disclosed |
| US-9485989-B2 | Method of controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-08 | — | — | US | disclosed |
| US-9485989-B2 | Method of controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-08 | — | — | US | disclosed |
| US-9462808-B2 | Pesticidal compositions | SYNGENTA PARTICIPANTS AG (CH) | 2016-10-11 | — | — | US | disclosed |
| US-9462808-B2 | Pesticidal compositions | SYNGENTA PARTICIPANTS AG (CH) | 2016-10-11 | — | — | US | disclosed |
| US-20150259345-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA LIMITED (GB) | 2015-09-17 | — | — | US | disclosed |
| US-20150259345-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA LIMITED (GB) | 2015-09-17 | — | — | US | disclosed |
| US-9067892-B2 | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA CROP PROTECTION, INC. (US) | 2015-06-30 | — | — | US | disclosed |
| US-9067892-B2 | Spiroheterocyclic N-oxypiperidines as pesticides | SYNGENTA CROP PROTECTION, INC. (US) | 2015-06-30 | — | — | US | disclosed |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130150394-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-13 | — | — | US | disclosed |
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| US-20110301031-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301031-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-12-08 | — | — | US | disclosed |
| WO-2011151247-A2 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151194-A1 | 1, 8 -DIAZASPIRO [4.5] DECANE- 2, 4 -DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151248-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2010066780-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301031-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | DDT, THOP1, KCNH1 | ACACB 2863/4885ACACA 2333/4885HTR2A 1134/4885 |
| US-20130150394-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, GAP43 | ACACB 2218/4885ACACA 2406/4885HTR2A 3560/4885 |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | DDT, CIP2A, CYP51A1 | ACACB 2493/4885ACACA 3320/4885HTR2A 4585/4885 |
| US-20150259345-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | DDT, THOP1, KCNH1 | ACACB 2745/4885ACACA 2349/4885HTR2A 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.