Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1049963 | 0.83 | PARP1 (0.56) | PARP1SMN1; SMN2KMT2AMEN1S100A4 | |
| SCHEMBL767178 | 0.74 | MEN1 (0.63) | PARP1SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL505409 | 0.73 | S100A4 (0.55) | SMN1; SMN2KMT2AMEN1S100A4POLB | |
| SCHEMBL9290363 | 0.73 | BCHE (0.51) | SMN1; SMN2KMT2AMEN1POLBNPC1 | |
| SCHEMBL9079985 | 0.72 | MEN1 (0.52) | SMN1; SMN2KMT2AMEN1POLBNPSR1 | |
| Pyrene SCHEMBL28900225 | 0.72 | PARP1 (0.91) | PARP1SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL57038 | 0.71 | PARP1 (1.00) | PARP1SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL2487811 | 0.71 | PARP1 (1.00) | PARP1SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL14257644 | 0.71 | S100A4 (0.61) | SMN1; SMN2KMT2AMEN1S100A4POLB | |
| SCHEMBL17529463 | 0.71 | NPSR1 (0.49) | PARP1SMN1; SMN2KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227621-B2 | Cyanine dyes and methods of use | LI-COR, INC. (US) | 2012-07-24 | — | — | US | disclosed |
| EP-1910554-A2 | CYANINE DYES AND METHODS OF USE IN BIOLOGICAL APPLICATIONS | LI-COR, INC. (US) | 2008-04-16 | — | — | EP | disclosed |
| US-20070042398-A1 | CYANINE DYES AND METHODS OF USE | LI-COR, INC. (US) | 2007-02-22 | — | — | US | disclosed |
| WO-2007005222-A2 | CYANINE DYES AND METHODS OF USE IN BIOLOGICAL APPLICATIONS | LI-COR, INC. (US) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070042398-A1 | CYANINE DYES AND METHODS OF USE | CRY2, IK, CRY1 | PARP1 977/4885SMN1; SMN2 4748/4885KMT2A 3439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.