Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | ESRRG | P62508 | 2/20 | 0.30 |
| ▸ | ESRRB | O95718 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580187 | 0.83 | LMNA (0.37) | F10LMNAALDH1A1LPAR1SMN1; SMN2 | |
| SCHEMBL3581435 | 0.75 | TP53 (0.41) | F10LMNASERPINE1LPAR1F2 | |
| SCHEMBL9958710 | 0.75 | LPAR1 (0.38) | ALDH1A1LPAR1LPAR2F2SMN1; SMN2 | |
| SCHEMBL3581531 | 0.74 | C5AR1 (0.43) | F10LMNAALDH1A1SERPINE1LPAR1 | |
| SCHEMBL4611556 | 0.74 | KMT2A (0.35) | LMNALPAR1MAPTHSP90AA1ESRRG | |
| SCHEMBL3576346 | 0.73 | CNR1 (0.38) | F10LPAR1LPAR2MAPTCNR1 | |
| SCHEMBL3583318 | 0.72 | HSPH1 (0.44) | LMNALPAR1SMN1; SMN2CNR1 | |
| SCHEMBL3583634 | 0.72 | SERPINE1 (0.39) | LMNAALDH1A1SERPINE1MAPTSMN1; SMN2 | |
| SCHEMBL3584396 | 0.71 | C5AR1 (0.44) | F10LMNAALDH1A1SERPINE1LPAR1 | |
| SCHEMBL3571600 | 0.70 | LMNA (0.42) | LMNASERPINE1LPAR1SMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984340-A1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007090752-A1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-16 | — | — | WO | disclosed |