Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581565 | 0.79 | SLC2A1 (0.43) | LPAR1LPAR2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4614116 | 0.76 | ALDH1A1 (0.33) | LPAR1LPAR2ALDH1A1GLALPAR5 | |
| SCHEMBL4612209 | 0.75 | F10 (0.34) | LPAR1LPAR2ALDH1A1F2SMN1; SMN2 | |
| SCHEMBL3572707 | 0.72 | CCR9 (0.42) | LPAR1LPAR2ALDH1A1CYP3A4GLA | |
| SCHEMBL3569645 | 0.72 | CCR9 (0.43) | LPAR1LPAR2ALDH1A1GLACCR9 | |
| SCHEMBL3577563 | 0.72 | NLRP3 (0.42) | LPAR1LPAR2ALDH1A1GLALPAR5 | |
| SCHEMBL3584106 | 0.71 | LPAR1 (0.59) | LPAR1LPAR2LPAR5 | |
| SCHEMBL3577662 | 0.71 | LPAR1 (0.43) | LPAR1LPAR2ALDH1A1GLASMN1; SMN2 | |
| SCHEMBL3569038 | 0.70 | LPAR1 (0.40) | LPAR1LPAR2ALDH1A1GLACCR9 | |
| SCHEMBL3577159 | 0.69 | C5AR1 (0.42) | LPAR1LPAR2ALDH1A1GLALPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |