Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4803335 | 0.87 | L3MBTL1 (0.40) | EPHX2PPARGALDH1A1LMNAPOLB | |
| SCHEMBL4803342 | 0.87 | L3MBTL1 (0.40) | EPHX2PPARGALDH1A1LMNAPOLB | |
| SCHEMBL4804598 | 0.82 | EPHX2 (0.35) | EPHX2PPARGALDH1A1LMNAPOLB | |
| SCHEMBL4804601 | 0.82 | EPHX2 (0.35) | EPHX2PPARGALDH1A1LMNAPOLB | |
| SCHEMBL4805760 | 0.78 | NFKB1 (0.33) | EPHX2PPARGALDH1A1LMNAPOLB | |
| SCHEMBL4805755 | 0.78 | NFKB1 (0.33) | EPHX2PPARGALDH1A1LMNAPOLB | |
| SCHEMBL4796480 | 0.76 | ALDH1A1 (0.49) | EPHX2PPARGALDH1A1LMNAPOLB | |
| SCHEMBL4612257 | 0.74 | TSHR (0.47) | TDP1EPHX2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL29404427 | 0.73 | TSHR (0.48) | TDP1EPHX2ALDH1A1LMNATSHR | |
| SCHEMBL28338208 | 0.73 | TSHR (0.48) | TDP1EPHX2ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833788-B1 | PROCESS FOR PREPARING PERINDOPRIL ERBUMINE | SINT QUIMICA SA (ES) | 2008-04-16 | — | — | EP | disclosed |
| EP-1833788-A1 | PROCESS FOR PREPARING PERINDOPRIL ERBUMINE | Quimica Sintetica, S.A. (ES) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006070276-A1 | PROCESS FOR PREPARING PERINDOPRIL ERBUMINE | QUIMICA SINTETICA, S.A. (ES) | 2006-07-06 | — | — | WO | disclosed |