Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46375 | 0.85 | NPSR1 (0.31) | POLBSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL19140029 | 0.85 | P2RX7 (0.30) | — | |
| SCHEMBL37643 | 0.84 | FFAR4 (0.33) | — | |
| SCHEMBL12574763 | 0.83 | — | — | |
| SCHEMBL12574772 | 0.81 | RAB9A (0.36) | POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL46114 | 0.77 | MEN1 (0.33) | POLBMEN1ALDH1A1KMT2A | |
| SCHEMBL37723 | 0.75 | KCNH2 (0.34) | SMN1; SMN2MEN1ALDH1A1KMT2AOPRM1 | |
| SCHEMBL12574778 | 0.75 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL12071745 | 0.75 | EZH2 (0.32) | POLBMEN1ALDH1A1KMT2A | |
| SCHEMBL46100 | 0.75 | EPHX2 (0.34) | POLBMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2010063670-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-10 | — | — | WO | disclosed |