Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46114 | 0.92 | MEN1 (0.33) | MEN1KMT2AALDH1A1EPHX2POLB | |
| SCHEMBL12071745 | 0.89 | EZH2 (0.32) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL46100 | 0.89 | EPHX2 (0.34) | MEN1KMT2AALDH1A1EPHX2FFAR4 | |
| SCHEMBL12574763 | 0.88 | — | — | |
| SCHEMBL46054 | 0.87 | L3MBTL1 (0.30) | — | |
| SCHEMBL46353 | 0.87 | LMNA (0.32) | NPSR1ALDH1A1 | |
| SCHEMBL46053 | 0.87 | SIGMAR1 (0.32) | MEN1KMT2AALDH1A1 | |
| SCHEMBL12573600 | 0.85 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL46126 | 0.85 | POLB (0.31) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL46140 | 0.84 | TSHR (0.32) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2010066780-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-17 | — | — | WO | disclosed |