Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 8/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612427 | 0.94 | GRN (0.33) | HTRA1ANO1 | |
| SCHEMBL4613305 | 0.88 | HTRA1 (0.34) | HTRA1KMT2AKDM4EGAA | |
| SCHEMBL4613689 | 0.84 | SMN1; SMN2 (0.33) | KDM4E | |
| SCHEMBL5160918 | 0.84 | HTRA1 (0.35) | HTRA1 | |
| SCHEMBL4614473 | 0.84 | HTRA1 (0.33) | HTRA1 | |
| SCHEMBL6252988 | 0.83 | HTRA1 (0.31) | HTRA1 | |
| SCHEMBL4612394 | 0.82 | GRN (0.33) | HTRA1KMT2AANO1 | |
| SCHEMBL4616219 | 0.82 | PKM (0.35) | HTRA1KMT2AANO1GAALMNA | |
| SCHEMBL11439707 | 0.78 | TSHR (0.36) | KMT2AANO1CACNA1HKDM4EGAA | |
| SCHEMBL4614038 | 0.77 | TSHR (0.35) | HTRA1KMT2AKDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567480-B1 | N-ALKYNYL-2-(SUBSTITUTED PHENOXY) ALKYLAMIDES AND THEIR USE AS FUNGICIDES | SYNGENTA LTD (GB) | 2008-03-12 | — | — | EP | disclosed |
| US-7271130-B2 | N-alkynyl-2-(substituted phenoxy) alkylamides and their use as fungicides | SYNGENTA LIMITED (GB) | 2007-09-18 | — | — | US | disclosed |
| US-20060194763-A1 | N-alkynyl-2-(substituted phenoxy) alkylamides and their use as fungicides | SYNGENTA LIMITED (GB) | 2006-08-31 | — | — | US | disclosed |
| EP-1567480-A1 | N-ALKYNYL-2-(SUBSTITUTED PHENOXY) ALKYLAMIDES AND THEIR USE AS FUNGICIDES | Syngenta Limited (GB) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048316-A1 | N-ALKYNYL-2- (SUBSTITUTED PHENOXY) ALKYLAMIDES AND THEIR USE AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194763-A1 | N-alkynyl-2-(substituted phenoxy) alkylamides and their use as fungicides | CYP4X1, PRXL2A, CYP1A2 | HTRA1 2403/4885KMT2A 327/4885ANO1 872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.