Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | OGG1 | O15527 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602647 | 0.89 | OGG1 (0.45) | POLBGAANPSR1ALDH1A1TSHR | |
| SCHEMBL5160452 | 0.88 | PKM (0.35) | PKM | |
| SCHEMBL4612427 | 0.88 | GRN (0.33) | ALDH1A1CARM1PRMT6ANO1HTRA1 | |
| SCHEMBL5160782 | 0.88 | PKM (0.36) | PKMPOLBGAANPSR1ALDH1A1 | |
| SCHEMBL11511635 | 0.87 | POLB (0.34) | PKMPOLBGAANPSR1ALDH1A1 | |
| SCHEMBL6250808 | 0.87 | POLB (0.34) | PKMPOLBGAANPSR1ALDH1A1 | |
| SCHEMBL3946333 | 0.87 | PKM (0.32) | PKMPOLBGAANPSR1ALDH1A1 | |
| SCHEMBL3940781 | 0.87 | TSHR (0.33) | PKMPOLBGAANPSR1ALDH1A1 | |
| SCHEMBL11528939 | 0.87 | NPSR1 (0.38) | PKMPOLBNPSR1ALDH1A1TSHR | |
| SCHEMBL6249581 | 0.86 | TSHR (0.32) | PKMPOLBGAANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146387-A | COMPRISING AN ALKYNYL-AMIDE AND A HALOACETANILIDE | STAUFFER CHEMICAL COMPANY (US) | 1979-03-27 | — | — | US | claimed |
| EP-1567005-B1 | FUNGICIDES | SYNGENTA LTD (GB) | 2008-02-20 | — | — | EP | disclosed |
| US-20060058397-A1 | Fungicides | SYNGENTA LIMITED (GB) | 2006-03-16 | — | — | US | disclosed |
| EP-1567005-A1 | FUNGICIDES | Syngenta Limited (GB) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004047537-A1 | FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-06-10 | — | — | WO | disclosed |
| US-4146387-A | COMPRISING AN ALKYNYL-AMIDE AND A HALOACETANILIDE | STAUFFER CHEMICAL COMPANY (US) | 1979-03-27 | — | — | US | disclosed |
| US-4116677-A | N-alkyl-alpha-(substituted phenoxy) alkylamides and their use as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058397-A1 | Fungicides | CYP4X1, CYP1A1, CYP4Z1 | PKM 2997/4885POLB 4056/4885GAA 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.