Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 2/20 | 0.31 |
| ▸ | GRN | P28799 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249581 | 0.91 | TSHR (0.32) | ALDH1A1 | |
| SCHEMBL4612427 | 0.89 | GRN (0.33) | HTRA1GRNSORT1ALDH1A1 | |
| SCHEMBL4612652 | 0.83 | HTRA1 (0.32) | HTRA1 | |
| SCHEMBL6250848 | 0.82 | ALDH1A1 (0.33) | GRNSORT1ALDH1A1 | |
| SCHEMBL6671901 | 0.81 | HTRA1 (0.32) | HTRA1 | |
| SCHEMBL4612394 | 0.79 | GRN (0.33) | HTRA1GRNSORT1ALDH1A1 | |
| SCHEMBL4614473 | 0.79 | HTRA1 (0.33) | HTRA1GRNSORT1ALDH1A1 | |
| SCHEMBL6252253 | 0.78 | NPSR1 (0.32) | — | |
| SCHEMBL6173111 | 0.78 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL6253709 | 0.78 | PKM (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567480-A1 | N-ALKYNYL-2-(SUBSTITUTED PHENOXY) ALKYLAMIDES AND THEIR USE AS FUNGICIDES | Syngenta Limited (GB) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048316-A1 | N-ALKYNYL-2- (SUBSTITUTED PHENOXY) ALKYLAMIDES AND THEIR USE AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-06-10 | — | — | WO | disclosed |