SCHEMBL4613236

SCHEMBL4613236

O=C(NC(=O)[C@@H]1CCCN1)c1ccc2ccccc2c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
LDHA P00338 1/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
KDM4A O75164 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
KDM4C Q9H3R0 1/20 0.43
PLG P00747 2/20 0.43
KLK1 P06870 2/20 0.43
KLK6 Q92876 2/20 0.43
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
HTR2C P28335 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9394978 0.86 MMP3 (0.48) KMT2AKDM4ELMNANPC1ALDH1A1
SCHEMBL27930384 0.78 FURIN (0.39) PLGKLK1KLK6HTR2CHTR2B
SCHEMBL8419532 0.76 PLK1 (0.53) KMT2AKDM4EMAPTLMNAHTT
SCHEMBL7511740 0.76 GPR6 (0.46) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL13570471 0.76 GID4 (0.45) KDM4ELMNAHTR2CHTR2BCTSC
SCHEMBL7517030 0.76 CDC25B (0.46) KDM4ERAB9AHTR2CHTR2B
SCHEMBL8397188 0.74 CTSC (0.49) NPC1RAB9AGAAHTR2CHTR2B
SCHEMBL13570411 0.74 HDAC8 (0.50) MEN1KMT2AKDM4EMAPTLMNA
SCHEMBL12348757 0.73 ROCK2 (0.48) MEN1KMT2AKDM4EALDH1A1HTR2C
SCHEMBL13570574 0.73 ROCK2 (0.43) KMT2AKDM4ERAB9AGAAHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050095660-A1 Enzyme activities and pH tests for the determination of the risk of obstetric and gynecologic complications in samples of body fluids of women UNIBIO, S.R.I. (IT) 2005-05-05 US claimed
EP-1528396-A1 Enzyme activities and pH tests for the determination of the risk of obstetric and gynecologic complications in samples of body fluids of women UNIBIO S.R.L. (IT) 2005-05-04 EP claimed
US-20040219617-A1 Enzymatic test for the determination of the risk of pathologies related to the presence of sialidase or prolidase activity in women body fluid samples UNIBIO S.R.L. (IT) 2004-11-04 US claimed
EP-1360484-A1 ENZYMATIC TEST FOR THE DETERMINATION OF THE RISK OF PATHOLOGIES RELATED TO THE PRESENCE OF SIALIDASE OR PROLIDASE ACTIVITY IN WOMEN BODY FLUID SAMPLES UNIBIO S.R.L. (IT) 2003-11-12 EP claimed
WO-2002065122-A1 ENZYMATIC TEST FOR THE DETERMINATION OF THE RISK OF PATHOLOGIES RELATED TO THE PRESENCE OF SIALIDASE OR PROLIDASE ACTIVITY IN WOMEN BODY FLUID SAMPLES UNIBIO S.R.L. (IT) 2002-08-22 WO claimed
US-5571684-A SOLID PHASE CONJUGATE LITMUS CONCEPTS, INC. (US) 1996-11-05 US claimed
EP-1360484-B1 ENZYMATIC TEST FOR THE DETERMINATION OF THE RISK OF PATHOLOGIES RELATED TO THE PRESENCE OF SIALIDASE OR PROLIDASE ACTIVITY IN WOMEN BODY FLUID SAMPLES UNIBIO S R L (IT) 2008-10-29 EP disclosed
CN-1637150-A Activities and ph tests for the determination of the risk of obstetric and gynecologic complications UNIBIO S R I (IT) 2005-07-13 CN disclosed
US-20050095660-A1 Enzyme activities and pH tests for the determination of the risk of obstetric and gynecologic complications in samples of body fluids of women UNIBIO, S.R.I. (IT) 2005-05-05 US disclosed
EP-1528396-A1 Enzyme activities and pH tests for the determination of the risk of obstetric and gynecologic complications in samples of body fluids of women UNIBIO S.R.L. (IT) 2005-05-04 EP disclosed
US-20040219617-A1 Enzymatic test for the determination of the risk of pathologies related to the presence of sialidase or prolidase activity in women body fluid samples UNIBIO S.R.L. (IT) 2004-11-04 US disclosed
EP-1360484-A1 ENZYMATIC TEST FOR THE DETERMINATION OF THE RISK OF PATHOLOGIES RELATED TO THE PRESENCE OF SIALIDASE OR PROLIDASE ACTIVITY IN WOMEN BODY FLUID SAMPLES UNIBIO S.R.L. (IT) 2003-11-12 EP disclosed
WO-2002065122-A1 ENZYMATIC TEST FOR THE DETERMINATION OF THE RISK OF PATHOLOGIES RELATED TO THE PRESENCE OF SIALIDASE OR PROLIDASE ACTIVITY IN WOMEN BODY FLUID SAMPLES UNIBIO S.R.L. (IT) 2002-08-22 WO disclosed
WO-2000065347-A9 MULTIPLE DIAGNOSTIC DEVICE FOR A WOMAN'S HEALTH PROCTER & GAMBLE (US) 2002-02-21 WO disclosed
EP-1173758-A2 MULTIPLE DIAGNOSTIC DEVICE FOR A WOMAN'S HEALTH The Procter & Gamble Company (US) 2002-01-23 EP disclosed
WO-2000065347-A2 MULTIPLE DIAGNOSTIC DEVICE FOR A WOMAN'S HEALTH THE PROCTER & GAMBLE COMPANY (US) 2000-11-02 WO disclosed
EP-0791071-B1 ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES LITMUS CONCEPTS INC (US) 1999-09-15 EP disclosed
EP-0791071-A1 ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES LITMUS CONCEPTS, INC. (US) 1997-08-27 EP disclosed
US-5571684-A SOLID PHASE CONJUGATE LITMUS CONCEPTS, INC. (US) 1996-11-05 US disclosed
WO-1996015255-A2 ASSAY FOR PROLINE IMINOPEPTIDASE AND OTHER HYDROLYTIC ACTIVITIES LITMUS CONCEPTS, INC. (US) 1996-05-23 WO disclosed