Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA6 | P23280 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27875230 | 0.98 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TDP1TRPV4GAA | |
| SCHEMBL18421177 | 0.98 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TDP1TRPV4GAA | |
| SCHEMBL250199 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HSD17B10TDP1TRPV4GAA | |
| SCHEMBL30948577 | 0.79 | GAA (0.50) | ALDH1A1GAACA1CA2CA6 | |
| SCHEMBL3279998 | 0.79 | GAA (0.50) | ALDH1A1GAACA1CA2CA6 | |
| SCHEMBL29644921 | 0.75 | BCAT2 (0.40) | ALDH1A1GAACA1CA2CA6 | |
| SCHEMBL1048970 | 0.75 | TSHR (0.44) | ALDH1A1TDP1GAACA1CA2 | |
| SCHEMBL1806991 | 0.75 | CA2 (0.56) | GAACA1CA2CA6CA9 | |
| SCHEMBL944099 | 0.75 | BCAT2 (0.40) | ALDH1A1GAACA1CA2CA6 | |
| SCHEMBL10415459 | 0.74 | GAA (0.50) | ALDH1A1HSD17B10TDP1TRPV4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111234803-A | Ligand exchange method of quantum dots and quantum dot compound | TCL集团股份有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-111234803-A | Ligand exchange method of quantum dots and quantum dot compound | TCL集团股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-105381573-B | Golf | 邓禄普体育用品株式会社 | 2018-03-09 | — | — | CN | disclosed |
| EP-2668975-B1 | Golf ball | DUNLOP SPORTS CO LTD (JP) | 2017-07-19 | — | — | EP | disclosed |
| CN-103446720-B | Golf ball | 邓禄普体育用品株式会社 | 2017-05-10 | — | — | CN | disclosed |
| EP-2669328-B1 | Golf ball | DUNLOP SPORTS CO LTD (JP) | 2017-03-22 | — | — | EP | disclosed |
| EP-2668977-B1 | Golf ball | DUNLOP SPORTS CO LTD (JP) | 2017-02-01 | — | — | EP | disclosed |
| CN-103446725-B | Golf | 邓禄普体育用品株式会社 | 2016-08-10 | — | — | CN | disclosed |
| CN-103418115-B | Golf | DUNLOP SPORTS CO., LTD. (JP) | 2016-05-11 | — | — | CN | disclosed |
| CN-103418116-B | Golf | DUNLOP SPORTS CO., LTD. (JP) | 2016-05-04 | — | — | CN | disclosed |
| CN-103372285-A | Golf ball | DUNLOP SPORTS CO LTD | 2013-10-30 | — | — | CN | disclosed |
| CN-102526997-A | Golf ball | SRI SPORTS LTD | 2012-07-04 | — | — | CN | disclosed |
| CN-102526995-A | Golf ball | SRI SPORTS LTD | 2012-07-04 | — | — | CN | disclosed |
| CN-102485294-A | Golf ball | SRI SPORTS LTD | 2012-06-06 | — | — | CN | disclosed |
| EP-1599477-B1 | SULFONAMIDE SUBSTITUTED XANTHINE DERIVATIVES FOR USE AS PEPCK INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-01-30 | — | — | EP | disclosed |
| US-7148229-B2 | Sulfonamide substituted xanthine derivatives | HOFFMAN-LA ROCHE INC. (US) | 2006-12-12 | — | — | US | disclosed |
| EP-1599477-A1 | SULFONAMIDE SUBSTITUTED XANTHINE DERIVATIVES FOR USE AS PEPCK INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-11-30 | — | — | EP | disclosed |
| US-20040192708-A1 | Sulfonamide substituted xanthine derivatives | DUNTEN PETER W (US) | 2004-09-30 | — | — | US | disclosed |
| WO-2004074288-A1 | SULFONAMIDE SUBSTITUTED XANTHINE DERIVATIVES FOR USE AS PEPCK INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-02 | — | — | WO | disclosed |
| CN-1335834-A | Aromatic heterocyclic compounds having HIV integrase inhibitory activity | SHIONOGI & CO (JP) | 2002-02-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192708-A1 | Sulfonamide substituted xanthine derivatives | GYS2, SLC5A1, SLC5A2 | ALDH1A1 277/4885HSD17B10 293/4885TDP1 2475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.