Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL618431 | 0.77 | — | — | |
| SCHEMBL6152260 | 0.73 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL4612505 | 0.72 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTCYP2C9CYP2C19 | |
| SCHEMBL10268749 | 0.72 | — | — | |
| SCHEMBL7254407 | 0.64 | NPC1 (0.37) | ALDH1A1KDM4EMAPTPOLBNPC1 | |
| SCHEMBL22961722 | 0.64 | KDM4E (0.39) | ALDH1A1KDM4EHPGDMAPTPOLB | |
| SCHEMBL2737281 | 0.63 | — | — | |
| SCHEMBL12394785 | 0.61 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDMAPTPOLB | |
| SCHEMBL12461694 | 0.61 | ELANE (0.42) | ALDH1A1KDM4EHPGDMAPTPOLB | |
| SCHEMBL14465626 | 0.61 | KMT2A (0.40) | ALDH1A1KDM4EHPGDMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1281704-B1 | Process for the the preparation of substituted oxazoles in a continous manner | BASF AG (DE) | 2008-01-23 | — | — | EP | disclosed |
| US-7038058-B2 | Continuous preparation of substituted oxazoles | BASF AKTIENGESELLSCHAFT (DE) | 2006-05-02 | — | — | US | disclosed |
| US-6900332-B2 | Process for the preparation of substituted oxazoles | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-31 | — | — | US | disclosed |
| EP-1281703-B1 | Process for the preparation of 5-alkoxy-oxazoles as well as of pyridoxines | BASF AG (DE) | 2005-01-26 | — | — | EP | disclosed |
| US-20040110961-A1 | Continuous preparation of substituted oxazoles | DSM IP ASSETS B.V. (NL) | 2004-06-10 | — | — | US | disclosed |
| US-6713630-B2 | CYCLIZATION AND ACIDIFICATION OF 4-METHYL-5-N-BUTOXYOXAZOLE WITHIN TUBULAR REACTOR | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-30 | — | — | US | disclosed |
| US-20030125567-A1 | Process for the preparation of substituted oxazoles | DSM IP ASSETS B.V. (NL) | 2003-07-03 | — | — | US | disclosed |
| US-20030120082-A1 | Continuous preparation of substituted oxazoles | DSM IP ASSETS B.V. (NL) | 2003-06-26 | — | — | US | disclosed |
| US-20030050479-A1 | Converting alpha -isocyanoalkyl acid esters derivative in presence of a base into 5-alkoxy-substituted oxazoles and simultaneously to the conversion, separating the product from the reaction mixture | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-13 | — | — | US | disclosed |
| US-20030050478-A1 | Process for the continuous preparation of substituted oxazoles | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-13 | — | — | US | disclosed |
| EP-1281703-A1 | Process for the preparation of 5-alkoxy-oxazoles as well as of pyridoxines | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-05 | — | — | EP | disclosed |
| EP-1281704-A1 | Process for the the preparation of substituted oxazoles in a continous manner | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050479-A1 | Converting alpha -isocyanoalkyl acid esters derivative in presence of a base into 5-alkoxy-substituted oxazoles and simultaneously to the conversion, separating the product from the reaction mixture | PDXK, PNPO, CYP4B1 | ALDH1A1 262/4885KDM4E 470/4885HPGD 303/4885 |
| US-20030125567-A1 | Process for the preparation of substituted oxazoles | PNPO, PDXK, CYP3A5 | ALDH1A1 990/4885KDM4E 465/4885HPGD 320/4885 |
| US-20030120082-A1 | Continuous preparation of substituted oxazoles | PNPO, PDXK, PLPBP | ALDH1A1 811/4885KDM4E 461/4885HPGD 121/4885 |
| US-20040110961-A1 | Continuous preparation of substituted oxazoles | PNPO, PDXK, PLPBP | ALDH1A1 811/4885KDM4E 461/4885HPGD 121/4885 |
| US-20030050478-A1 | Process for the continuous preparation of substituted oxazoles | PNPO, PLPBP, PDXK | ALDH1A1 774/4885KDM4E 510/4885HPGD 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.