Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241643 | 0.78 | OXTR (0.42) | MAOAMAOBTSHROXTRABCG2 | |
| SCHEMBL29386319 | 0.70 | — | — | |
| SCHEMBL6093132 | 0.70 | — | — | |
| SCHEMBL8710 | 0.70 | — | — | |
| SCHEMBL730025 | 0.70 | — | — | |
| SCHEMBL5065 | 0.70 | MAOA (0.39) | MAOAMAOBOXTRABCG2ITGB2 | |
| SCHEMBL3682309 | 0.69 | MAOA (0.42) | MAOAMAOBTSHROXTRABCG2 | |
| Hydrochloric Acid SCHEMBL6762162 | 0.69 | MAOA (0.42) | MAOAMAOBTSHROXTRABCG2 | |
| Methane SCHEMBL10528050 | 0.69 | MAOA (0.42) | MAOAMAOBTSHROXTRABCG2 | |
| Ammonia Solution, Strong SCHEMBL3205764 | 0.69 | MAOA (0.42) | MAOAMAOBTSHROXTRABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981856-A2 | PYRIMIDINE DERIVATIVES | AstraZeneca AB (SE) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007085833-A2 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | WO | disclosed |