Sulfotep

Sulfotep

SCHEMBL1163901

CCC(=O)O.CCC(=O)O.CCOP(=S)(OCC)OP(=S)(OCC)OCC

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.46
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
PPARD Q03181 2/20 0.35
TSHR P16473 5/20 0.35
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 2/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP2D6 P10635 1/20 0.32
TP53 P04637 1/20 0.32
SOAT1 P35610 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfotep SCHEMBL7762968 1.00 FFAR3 (0.46) FFAR3MEN1KMT2ATDP1PPARD
Sulfotep SCHEMBL461502 0.91 TDP1 (0.39) MEN1KMT2ATDP1PPARDTSHR
Sulfotep SCHEMBL9651631 0.89 PPARD (0.39) FFAR3MEN1KMT2ATDP1PPARD
Sulfotep SCHEMBL11232718 0.88 MEN1 (0.38) MEN1KMT2ATDP1PPARDTSHR
Sulfotep SCHEMBL5016573 0.88 MEN1 (0.38) FFAR3MEN1KMT2ATDP1PPARD
Sulfotep SCHEMBL53003 0.86 ALOX15 (0.37) MEN1KMT2ATDP1PPARDTSHR
Sulfotep SCHEMBL11233341 0.86 MEN1 (0.36) MEN1KMT2ATDP1PPARDTSHR
Sulfotep SCHEMBL7767701 0.85 FFAR3 (0.52) FFAR3MEN1KMT2ATDP1PPARD
Sulfotep SCHEMBL1163295 0.85 FFAR3 (0.52) FFAR3MEN1KMT2ATDP1PPARD
Sulfotep SCHEMBL9401149 0.85 PTGS1 (0.36) MEN1KMT2ATDP1PPARDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2177236-B1 A METHOD FOR THE FORMATION OF A RAPID-GELLING BIOCOMPATIBLE HYDROGEL AND THE PREPARATION OF A SPRAYING AGENT BIOREGEN BIOMEDICAL CHANGZHOU (CN) 2016-11-02 EP claimed
US-8647670-B2 Biocompatible rapid-gelating hydrogel and associated preparation method of spray BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. (CN) 2014-02-11 US claimed
WO-2012057751-A1 CROSSLINKED CELLULOSIC POLYMERS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2012-05-03 WO claimed
US-20100144902-A1 BIOCOMPATIBLE RAPID-GELATING HYDROGEL AND ASSOCIATED PREPARATION METHOD OF SPRAY BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. (CN) 2010-06-10 US claimed
EP-2177236-A1 A METHOD FOR THE FORMATION OF A RAPID-GELLING BIOCOMPATIBLE HYDROGEL AND THE PREPARATION OF A SPRAYING AGENT Bioregen Biomedical (Changzhou) Co., Ltd. (CN) 2010-04-21 EP claimed
EP-0579089-B1 Polyether ester amide-sulfur vulcanized rubber compounds GOODYEAR TIRE & RUBBER (US) 1996-09-18 EP claimed
EP-0579089-A1 Polyether ester amide-sulfur vulcanized rubber compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1994-01-19 EP claimed
EP-0364389-B1 Nylon modified rubber composition GOODYEAR TIRE & RUBBER (US) 1993-12-08 EP claimed
US-5239004-A A curied addition-condensation copolymer grafted by at least one dithiodiacid; odorless, stiffness, tensile strength THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-08-24 US claimed
US-5202384-A Grafting polyester onto the rubber using a dithiodialkanoic acid; high modulus; stiffness; tensile strength; tire treads; no increased hysteresis THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-04-13 US claimed
EP-0390722-A2 Polyester reinforced rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-10-03 EP claimed
CN-1043397-A UV-curable composition for making solder mask coatings with coverability M & T CHEMICALS INC (US) 1990-06-27 CN claimed
US-4937290-A Improved modulus THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-06-26 US claimed
EP-0364389-A1 Nylon modified rubber composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-04-18 EP claimed
CN-115089720-B Tumor treatment medicine composition 沈阳药科大学 2023-12-26 CN disclosed
CN-116983421-A Adriamycin-fatty alcohol small molecule prodrug and construction of self-assembled nanoparticle thereof 沈阳信达泰康医药科技有限公司 2023-11-03 CN disclosed
CN-116239756-A Polyisocyanate composition stable in visible light and application thereof 万华化学集团股份有限公司 2023-06-09 CN disclosed
EP-0364389-A1 Nylon modified rubber composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-04-18 EP disclosed
US-4593043-A Mercapto acyl-carnitines and pharmaceutical compositions containing same SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1986-06-03 US disclosed
EP-0042768-A1 Injection molding and extrusion of ultra-high molecular weight polyethylene AMERICAN HOECHST CORPORATION (US) 1981-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100144902-A1 BIOCOMPATIBLE RAPID-GELATING HYDROGEL AND ASSOCIATED PREPARATION METHOD OF SPRAY CSTB, CAPG, F12 FFAR3 3729/4885MEN1 4328/4885KMT2A 4119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.