SCHEMBL4615296

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4616043	0.89	NPC1 (0.50)	PPARGPPARDESR1HPGDALDH1A1
	SCHEMBL4614599	0.83	RAB9A (0.49)	PPARGPPARDHPGDALDH1A1KDM4E
	SCHEMBL12093638	0.77	ALDH1A1 (0.56)	PPARDESR1HPGDALDH1A1KDM4E
	SCHEMBL2434899	0.75	ESR1 (0.53)	ESR1HPGDALDH1A1KDM4EGAA
	SCHEMBL726592	0.73	AKR1C3 (0.62)	ALDH1A1KDM4EKMT2AMEN1POLB
	SCHEMBL5416139	0.73	CYP1A2 (0.68)	ESR1HPGDALDH1A1GAAKMT2A
	SCHEMBL29843916	0.72	ESR1 (0.59)	ESR1HPGDALDH1A1KDM4EGAA
	SCHEMBL9130182	0.72	GAA (0.62)	HPGDALDH1A1KDM4EGAAMAPT
	SCHEMBL6503348	0.72	ESR1 (0.59)	ESR1HPGDALDH1A1KDM4EGAA
	SCHEMBL364241	0.72	HPGD (0.56)	HPGDALDH1A1KDM4EKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.