Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511836 | 0.85 | ALDH1A1 (0.83) | ALDH1A1LMNACA9CYP2C9CA1 | |
| SCHEMBL12181468 | 0.84 | ALDH1A1 (0.68) | ALDH1A1LMNACYP2C9CA2KMT2A | |
| SCHEMBL10645456 | 0.82 | ALDH1A1 (0.70) | ALDH1A1LMNACYP2C9CA2KMT2A | |
| SCHEMBL4615715 | 0.82 | HTR6 (0.53) | ALDH1A1LMNAPSIP1CA9CYP2C9 | |
| SCHEMBL30493991 | 0.81 | ALDH1A1 (0.63) | ALDH1A1LMNACYP2C9KMT2ATSHR | |
| SCHEMBL28859611 | 0.81 | ALDH1A1 (0.63) | ALDH1A1LMNACA9CYP2C9CA1 | |
| SCHEMBL28317568 | 0.81 | CYP3A4 (0.70) | ALDH1A1PSIP1CA9CA1CA2 | |
| SCHEMBL10476295 | 0.81 | ALDH1A1 (0.63) | ALDH1A1LMNACYP2C9KMT2ATSHR | |
| SCHEMBL20946436 | 0.80 | ALDH1A1 (0.73) | ALDH1A1LMNAPSIP1CA9CA1 | |
| SCHEMBL923761 | 0.80 | CA1 (0.72) | ALDH1A1LMNACA9CYP2C9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633714-B1 | 2-AMINO-PYRIDINE DERIVATIVES AS BETA-2 ADRENORECEPTOR AGONISTS | PFIZER LTD (GB) | 2008-01-23 | — | — | EP | disclosed |
| EP-1633714-B1 | 2-AMINO-PYRIDINE DERIVATIVES AS BETA-2 ADRENORECEPTOR AGONISTS | PFIZER LTD (GB) | 2008-01-23 | — | — | EP | disclosed |
| US-7067541-B2 | 2-amino-pyridine derivatives useful for the treatment of diseases | PFIZER INC (US) | 2006-06-27 | — | — | US | disclosed |
| US-20050004182-A1 | 2-Amino-pyridine derivatives useful for the treatment of diseases | PFIZER INC | 2005-01-06 | — | — | US | disclosed |
| EP-1313696-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-05-28 | — | — | EP | disclosed |
| US-20020035137-A1 | Amino (oxo) acetic acid protein tyrosine phosphatase inhibitors | ABBOTT LABORATORIES | 2002-03-21 | — | — | US | disclosed |
| WO-2002018323-A2 | AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035137-A1 | Amino (oxo) acetic acid protein tyrosine phosphatase inhibitors | PPM1A, PTPRO, PTP4A1 | ALDH1A1 299/4885LMNA 4772/4885PSIP1 3523/4885 |
| US-20050004182-A1 | 2-Amino-pyridine derivatives useful for the treatment of diseases | PAH, AADAT, IL4I1 | ALDH1A1 313/4885LMNA 2688/4885PSIP1 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.