Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5418540 | 0.98 | MAOA (0.38) | MAOAMAOBAPPMAPTALDH1A1 | |
| SCHEMBL6924125 | 0.92 | MAPK8 (0.36) | MAOAMAOBAPPMAPTALDH1A1 | |
| SCHEMBL21799681 | 0.91 | MAPT (0.39) | MAOAMAOBAPPMAPTALDH1A1 | |
| SCHEMBL21799622 | 0.86 | MAPK8 (0.46) | MAOAMAOBAPPMAPTALDH1A1 | |
| SCHEMBL6645052 | 0.85 | LATS1 (0.36) | MAOAMAOBAPPMAPTALDH1A1 | |
| SCHEMBL14594017 | 0.84 | APP (0.38) | MAOAMAOBAPPMAPTALDH1A1 | |
| SCHEMBL1636624 | 0.83 | MAPT (0.39) | MAOAMAOBAPPMAPTALDH1A1 | |
| SCHEMBL6921714 | 0.81 | LMNA (0.39) | MAOAMAOBAPPMAPTALDH1A1 | |
| SCHEMBL14253798 | 0.78 | MAOA (0.37) | MAOAMAOBAPPMAPTALDH1A1 | |
| SCHEMBL5400019 | 0.77 | APP (0.43) | MAOAMAOBAPPMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739074-B1 | Novel double para-phenylenediamines joined by a branched aliphatic group and use in dyeing | OREAL (FR) | 2008-03-12 | — | — | EP | disclosed |
| EP-1739074-B1 | Novel double para-phenylenediamines joined by a branched aliphatic group and use in dyeing | OREAL (FR) | 2008-03-12 | — | — | EP | disclosed |
| US-20070011828-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and method of dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011828-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and method of dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1739074-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739074-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011828-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and method of dyeing keratin fibers | KRT18, CDC73, DSP | MAOA 2800/4885MAOB 2834/4885APP 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.