Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4615465 | 0.83 | MAOA (0.39) | MAPTRAB9AMEN1KMT2AMAPK8 | |
| SCHEMBL21799622 | 0.83 | MAPK8 (0.46) | MAPTRAB9AMEN1KMT2AMAPK8 | |
| Hydrochloric Acid SCHEMBL5418540 | 0.81 | MAOA (0.38) | MAPTRAB9AMEN1KMT2AMAPK8 | |
| SCHEMBL14594017 | 0.81 | APP (0.38) | MAPTRAB9AMEN1KMT2AMAPK8 | |
| SCHEMBL21799681 | 0.79 | MAPT (0.39) | MAPTRAB9AMEN1KMT2AMAPK8 | |
| SCHEMBL6921714 | 0.78 | LMNA (0.39) | MAPTRAB9AMEN1KMT2AMAPK8 | |
| SCHEMBL6654223 | 0.77 | ESR1 (0.40) | MAPTMEN1KMT2ACA12CA1 | |
| SCHEMBL6924125 | 0.76 | MAPK8 (0.36) | MAPTRAB9AMEN1KMT2AMAPK8 | |
| SCHEMBL14253798 | 0.75 | MAOA (0.37) | MAPTRAB9AMEN1KMT2AMAOA | |
| SCHEMBL5400019 | 0.74 | APP (0.43) | MAPTRAB9AMEN1KMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106924056-B | Cosmetic composition for keratin fibers | 莱雅公司 | 2021-03-09 | — | — | CN | disclosed |
| US-9907743-B2 | Composition comprising (2,5-diaminophenyl)ethanol, an alkylpolyglucoside nonionic surfactant, an oxyethylenated sorbitan ester or a polyalkoxylated or polyglycerolated fatty alcohol in a medium rich in fatty substances, dyeing process and device therefor | L'OREAL (FR) | 2018-03-06 | — | — | US | disclosed |
| US-20150202142-A1 | DYEING COMPOSITION COMPRISING AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE OXIDIZING AGENT AND AT LEAST ONE NON-IONIC, ANIONIC AND AMPHOTERIC SURFACTANT | L'OREAL (FR) | 2015-07-23 | — | — | US | disclosed |
| US-20150082554-A1 | COMPOSITION COMPRISING (2,5-DIAMINOPHENYL)ETHANOL, AN ALKYLPOLYGLUCOSIDE NONIONIC SURFACTANT, AN OXYETHYLENATED SORBITAN ESTER OR A POLYALKOXYLATED OR POLYGLYCEROLATED FATTY ALCOHOL IN A MEDIUM RICH IN FATTY SUBSTANCES, DYEING PROCESS AND DEVICE THEREFOR | L'OREAL (FR) | 2015-03-26 | — | — | US | disclosed |
| US-8512419-B2 | Emulsion dyeing composition containing at least one phospholipid, at least one nonionic surfactant and at least one phosphate ester, and method of using same | L'OREAL (FR) | 2013-08-20 | — | — | US | disclosed |
| US-20120325243-A1 | EMULSION DYEING COMPOSITION CONTAINING AT LEAST ONE PHOSPHOLIPID, AT LEAST ONE NONIONIC SURFACTANT AND AT LEAST ONE PHOSPHATE ESTER, AND METHOD OF USING SAME | L'ORéAL S.A. (FR) | 2012-12-27 | — | — | US | disclosed |
| US-7931698-B2 | Ready-to-use composition for oxidation dyeing of keratin fibers comprising at least one fatty substance, at least one thickener, at least one dye precursor, at least one oxidizing agent, and at least one alkaline agent, and process and kits therewith | L'OREAL S.A. (FR) | 2011-04-26 | — | — | US | disclosed |
| US-20100154140-A1 | READY-TO-USE COMPOSITION FOR OXIDATION DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE THICKENER, AT LEAST ONE DYE PRECURSOR, AT LEAST ONE OXIDIZING AGENT, AND AT LEAST ONE ALKALINE AGENT, AND PROCESS AND KITS THEREWITH | L'OREAL S.A. (FR) | 2010-06-24 | — | — | US | disclosed |
| US-7722682-B2 | Composition for the oxidation dyeing of keratin fibers, comprising at least one fatty alcohol, at least one oxidation dye, at least one associative polymer, and at least one compound chosen from fatty acid esters and metal oxides | L'OREAL S.A. (FR) | 2010-05-25 | — | — | US | disclosed |
| US-20090180979-A1 | COMPOSITION FOR THE OXIDATION DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE CELLULOSE WITH HYDROPHOBIC SUBSTITUENTS, AT LEAST ONE OXIDATION DYE, AND AT LEAST ONE LONG-CHAIN FATTY ALCOHOL, AND METHODS OF USE THEREOF | L'OREAL S.A. (FR) | 2009-07-16 | — | — | US | disclosed |
| US-7204859-B2 | Composition for the oxidation dyeing of keratin fibers, comprising at least one fatty alcohol, at least one oxidation dye, at least one associative polymer, and at least one compound chosen from fatty acid esters and metal oxides | L'OREAL S.A. (FR) | 2007-04-17 | — | — | US | disclosed |
| US-20060277693-A1 | Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler and at least one associative polyurethane polymer | L'OREAL S.A. (FR) | 2006-12-14 | — | — | US | disclosed |
| US-6946005-B2 | Pyrrolidinyl-substituted para-phenylenediamine derivatives substituted with a cationic radical, and use of these derivatives for dyeing keratin fibers | L'OREAL S.A. (FR) | 2005-09-20 | — | — | US | disclosed |
| US-20050172422-A1 | Dye composition comprising at least one direct dye of the azo-pyridinio-pyridone family and at least one different synthetic dye, and process | L'OREAL S.A. (FR) | 2005-08-11 | — | — | US | disclosed |
| US-20040205902-A1 | Composition for the oxidation dyeing of keratin fibers, comprising at least one non-oxyalkenylated fatty alcohol, at least one oxidation dye, at least one associative polymer, and at least one amide of an alkanolamine and a C14-C30 fatty acid | L'OREAL S.A. (FR) | 2004-10-21 | — | — | US | disclosed |
| US-20040194227-A9 | Pyrrolidinyl-substituted para-phenylenediamine derivatives substituted with a cationic radical, and use of these derivatives for dyeing keratin fibres | L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | disclosed |
| US-20040172771-A1 | Composition for the oxidation dyeing of keratin fibers, comprising at least one fatty alcohol, at least one oxidation dye, at least one associative polymer, and at least one compound chosen from fatty acid esters and metal oxides | L'OREAL S.A. (FR) | 2004-09-09 | — | — | US | disclosed |
| US-6733540-B2 | FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-05-11 | — | — | US | disclosed |
| US-20030229949-A1 | Pyrrolidinyl-substituted para-phenylenediamine derivatives substituted with a cationic radical, and use of these derivatives for dyeing keratin fibres | SABELLE STEPHANE (FR) | 2003-12-18 | — | — | US | disclosed |
| US-20020100125-A1 | Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring | L'OREAL (FR) | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040172771-A1 | Composition for the oxidation dyeing of keratin fibers, comprising at least one fatty alcohol, at least one oxidation dye, at least one associative polymer, and at least one compound chosen from fatty acid esters and metal oxides | KRT18, FASN, ADH1A | MAPT 508/4885RAB9A 4268/4885MEN1 4297/4885 |
| US-20150082554-A1 | COMPOSITION COMPRISING (2,5-DIAMINOPHENYL)ETHANOL, AN ALKYLPOLYGLUCOSIDE NONIONIC SURFACTANT, AN OXYETHYLENATED SORBITAN ESTER OR A POLYALKOXYLATED OR POLYGLYCEROLATED FATTY ALCOHOL IN A MEDIUM RICH IN FATTY SUBSTANCES, DYEING PROCESS AND DEVICE THEREFOR | AKR1B10, FABP4, KRT18 | MAPT 1331/4885RAB9A 4815/4885MEN1 3809/4885 |
| US-20100154140-A1 | READY-TO-USE COMPOSITION FOR OXIDATION DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE THICKENER, AT LEAST ONE DYE PRECURSOR, AT LEAST ONE OXIDIZING AGENT, AND AT LEAST ONE ALKALINE AGENT, AND PROCESS AND KITS THEREWITH | KRT18, OAT, CKMT1A; CKMT1B | MAPT 1095/4885RAB9A 4551/4885MEN1 4055/4885 |
| US-20060277693-A1 | Composition for dyeing keratin fibers, comprising at least one diamino-N,N-dihydropyrazolone derivative, at least one coupler and at least one associative polyurethane polymer | KRT18, PRKDC, DSP | MAPT 896/4885RAB9A 4686/4885MEN1 3304/4885 |
| US-20150202142-A1 | DYEING COMPOSITION COMPRISING AT LEAST ONE FATTY SUBSTANCE, AT LEAST ONE OXIDIZING AGENT AND AT LEAST ONE NON-IONIC, ANIONIC AND AMPHOTERIC SURFACTANT | KRT18, DSG1, COXFA4 | MAPT 1704/4885RAB9A 4820/4885MEN1 4366/4885 |
| US-20040205902-A1 | Composition for the oxidation dyeing of keratin fibers, comprising at least one non-oxyalkenylated fatty alcohol, at least one oxidation dye, at least one associative polymer, and at least one amide of an alkanolamine and a C14-C30 fatty acid | KRT18, ACAD10, AKR1B10 | MAPT 1540/4885RAB9A 4543/4885MEN1 4757/4885 |
| US-20120325243-A1 | EMULSION DYEING COMPOSITION CONTAINING AT LEAST ONE PHOSPHOLIPID, AT LEAST ONE NONIONIC SURFACTANT AND AT LEAST ONE PHOSPHATE ESTER, AND METHOD OF USING SAME | PHOSPHO1, ALPP, ABHD16A | MAPT 1960/4885RAB9A 4233/4885MEN1 4375/4885 |
| US-20040194227-A9 | Pyrrolidinyl-substituted para-phenylenediamine derivatives substituted with a cationic radical, and use of these derivatives for dyeing keratin fibres | KRT18, VIM, CKAP4 | MAPT 903/4885RAB9A 3020/4885MEN1 4818/4885 |
| US-20030229949-A1 | Pyrrolidinyl-substituted para-phenylenediamine derivatives substituted with a cationic radical, and use of these derivatives for dyeing keratin fibres | KRT18, VIM, CKAP4 | MAPT 903/4885RAB9A 3020/4885MEN1 4818/4885 |
| US-20090180979-A1 | COMPOSITION FOR THE OXIDATION DYEING OF KERATIN FIBERS COMPRISING AT LEAST ONE CELLULOSE WITH HYDROPHOBIC SUBSTITUENTS, AT LEAST ONE OXIDATION DYE, AND AT LEAST ONE LONG-CHAIN FATTY ALCOHOL, AND METHODS OF USE THEREOF | KRT18, ADH5, ADH1C | MAPT 982/4885RAB9A 4127/4885MEN1 4789/4885 |
| US-20050172422-A1 | Dye composition comprising at least one direct dye of the azo-pyridinio-pyridone family and at least one different synthetic dye, and process | KRT18, KLK5, PLPBP | MAPT 799/4885RAB9A 4458/4885MEN1 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.