Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9910582 | 0.87 | CA5A (0.43) | CA5APRMT5KDM4EPTGDR2ALDH1A1 | |
| SCHEMBL10643826 | 0.76 | CA5A (0.40) | CA5AKDM4EALDH1A1PKMPKLR | |
| SCHEMBL9857412 | 0.73 | CA5A (0.55) | CA5AOPRM1OPRD1KDM4EALDH1A1 | |
| SCHEMBL9714161 | 0.73 | CA5A (0.48) | CA5AOPRM1OPRD1KDM4EALDH1A1 | |
| SCHEMBL9476992 | 0.72 | CA5A (0.53) | CA5AALDH1A1ADORA2AADORA1 | |
| SCHEMBL10662999 | 0.72 | LMNA (0.57) | ALDH1A1 | |
| SCHEMBL16824152 | 0.71 | CA5A (0.52) | CA5AOPRM1OPRD1KDM4EPTGDR2 | |
| SCHEMBL10662727 | 0.71 | CA5A (0.52) | CA5AOPRM1OPRD1KDM4EPTGDR2 | |
| SCHEMBL30281238 | 0.71 | HASPIN (0.36) | HSD11B1 | |
| SCHEMBL22125841 | 0.71 | MAPT (0.35) | KDM4EALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032540-A1 | PROCESS FOR PREPARATION OF FLUORINATED TRIAZOLE COMPOUND | INDOCO REMEDIES LIMITED (IN) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012032540-A1 | PROCESS FOR PREPARATION OF FLUORINATED TRIAZOLE COMPOUND | INDOCO REMEDIES LIMITED (IN) | 2012-03-15 | — | — | WO | disclosed |